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Biomedical subjects

M Jenett

Publications and source records attributed to M Jenett.

At least 37 records · Page 2Linked to original sources

[SieScape panorama imaging in radiologic diagnosis].

Through high-performance computer processing it has become possible to realize a new ultrasound imaging process: SieScape imaging. This method provides extended field of view images in real time using successive ultrasound images obtained when a standard transducer is scanned over a distance of up to 60 cm without any position sensor. SieScape offers new possibilities to view topographical anatomy. It is especially advantageous for scanning extended and tubular structures as well as large and enlarged organs and big pathologic volumes. Parallel scanning sequences allow documentation comparable to that of computed tomography. In addition, just as in magnetic resonance, variable imaging planes can be realized. The following describes the results obtained with SieScape in a multitude of clinical applications, especially in examinations of throat, thoracic and abdominal walls, breast, and intraabdominal organs as well as the soft tissues and small vessels of the extremities. The experience gathered with SieScape imaging--its advantages as well as its potential limitations, such as the formation of artefacts--is described.

Equipment Design↗

[In vitro studies to determine the degree of stenosis using spiral CT angiography].

UNLABELLED: Aim of the study was to evaluate the influence of different spiral-CT parameters for the visualisation of vascular stenoses, especially of the renal arteries. MATERIAL AND METHODS: Models with a density equivalent to that of fat, filled with diluted contrast agent, and an inner lumen of 4, 6, 8 mm were scanned in x-, y- and z-direction. Data were acquired in up to 24 second long spiral-CT scans using different spiral-CT parameters (collimation, table speed, reconstruction algorithm, tube current). Detection of the degree of stenosis was achieved by assessment of the axial images and 3D reconstructions. RESULTS: The best correlation between real and measured degree of stenosis was seen by using a small collimation, a low table increment and assessment of the axial images reconstructed in standard algorithm. The stenosis degrees of models directed in x- and y-direction were overestimated and those in z-direction were underestimated depending on the spiral-CT parameters. CONCLUSION: For optimal imaging of renal artery stenoses, collimation of 2 mm (pitch = 1-2 and a reconstruction interval of 1 mm is recommended.

Algorithms↗

[The stepchild of intestinal diagnosis. Evaluation of radiologic methods in the diagnosis of leiomyoma of the small intestine].

PURPOSE: Various radiological methods to diagnose small bowel neoplasms and problems of differential diagnosis specially considering leiomyomas are discussed. PATIENTS AND METHODS: Two patients with leiomyoma of the ileum underwent enteroclysis, computed tomography of the abdomen, intra-arterial DSA and colour Doppler sonography. Another patient with leiomyosarcoma just underwent CT of the abdomen with CT-guided biopsy. RESULTS: Due to the homogenous density and the smooth surface of the tumors in computed tomography and respectively enteroclysis and the presentation of the tumor vascularisation in the angiography and Colour Doppler sonography in both patients a leiomyoma of the small bowel was diagnosed. Postoperatively this diagnosis was histologically confirmed. The CT-findings of the patient with leiomyosarcoma were not suspicious of a malignant tumor. CONCLUSION: Radiologically it is not possible to determine the dignity of smooth muscle cell tumors safely. That is the reason why the diagnosis has to be achieved operatively. But the histopathological diagnosis based on the mitotic rate may be difficult. Therefore the after care has to be carried out thoroughly.

Aged↗

[Use of a PACS for ultrasound connection].

PURPOSE: This report describes the impact of a new digital picture archiving and communication system-PACS-in a diagnostic ultrasound department. The system consists of ultrasound workstations, a patient management workstation, a combined diagnostic workstation/archive server and a WWW client for standard PCs. Data exchange with other PAC-systems is possible via Ethernet. Staff required approximately 5 weeks to fully adjust to the new system. Following the adjustment period, documenting cases digitally reduced our exam times and improved our availability of images and reports for subsequent examinations, demonstrations, research and teaching. In the first year after installation, the new ultrasound PACS has proven its value in daily use.

Evaluation Studies as Topic↗

[Tertiary syphilis with liver gummata].

Sonography revealed multiple echo-poor lesions in the liver of a 51-year-old man with nonspecific symptoms (fatigue, drop in performance, pressure sensation in the upper abdomen), increased blood sedimentation rate (68/110 mm) and evidence of cholestasis (gamma-GT 126 U/l, alkaline phosphatase 444 U/l, leucine-aminopeptidase 64 U/l). Under the diagnosis of liver metastases the primary tumour was looked for. These investigations and a fine-needle biopsy having proved unsuccessful, laparoscopy was performed. The biopsies so obtained showed whitish yellow, tight elastic structures indicating gummas of the liver in tertiary syphilis. Treponema-specific IgM antibodies in serum characterized active syphilis requiring treatment. Administration of antibiotics (penicillin 1 mega U daily i.m.; because of allergy replaced after four days by erythromycin 2 g daily for six weeks) resulted in complete normalization of all biochemical findings and, some time later, regression of the gummas. The patient has now been symptom-free for three years. This case illustrates the need even to-day of including syphilis in the differential diagnosis of unclear space-occupying lesions of the liver.

Biopsy↗

[Digital image intensifier radiography and film-screen combinations in pulmonary nodules].

30 patients with known or suspected pulmonary nodules were examined using a digital image intensifier radiography system, a conventional radiography system and a tomography of the whole lung. 73.8% of the pulmonary nodules detected with tomography were also detected with the digital system, 69.1% with the conventional system. There was no significant difference between the two systems comparing false positive and false negative diagnoses. Regarding the dose reduction to nearly 25% of that of a conventional examination the digital technique should be preferred to the conventional technique, if pulmonary nodules are suspected.

Humans↗

111In-oxine-labelled white blood cells in the diagnosis and follow-up of Crohn's disease.

Prospectively, 43 patients with Crohn's disease (41 clinically active, 2 clinically inactive) and 7 patients with irritable bowel syndrome were examined by 111In-oxine-labelled leukocytes ('mixed' leukocyte preparations, n = 8; 'pure' granulocyte preparations, n = 42). The number of scintigraphically diagnosed inflamed bowel segments correlated significantly (r = 0.95, p less than 0.001) with the number of radiologically and endoscopically diagnosed segments. The exact localization of the diseased ileum may be difficult by scintigraphy. One complicating abscess and two fistulas were correctly diagnosed. The percentage of fecal excretion of radiolabelled leukocytes is highly specific for intestinal inflammations. It correlates significantly with the erythrocyte sedimentation rate (r = +0.69, p less than 0.001), serum albumin (r = -0.54, p less than 0.001), orosomucoid (r = +0.65, p less than 0.001), and with the A.I. (van Hees) (r = +0.67, p less than 0.001). In the follow-up of 9 patients, the percentage of fecal excretion decreased or increased more rapidly, but in correlation with the CDAI, A.I., or ESR. The authors conclude that this method is an alternative to common methods and that it is superior in primary diagnosis in patients with severe disease, bowel stenosis, abscesses, and after surgery. After clinical and biopsy-proven diagnosis of Crohn's disease, the special value of the leukocyte scan lies in the noninvasive follow-up of patients and its potential of localizing inflamed bowel segments and assessing disease activity.

Colon↗

[Scintigraphic diagnosis of inflammatory small bowel stenoses in Crohn disease using 111In oxine-labeled leukocytes].

17 patients with known small bowel involvement in Crohn's disease (clinically active, n = 14; clinically inactive, n = 3) were examined within 8 days via barium enemas of the small bowel (Pansdorf's method or enteroclysis) and by 111In-oxine labelled leucocytes. From 19 radiologically diagnosed small bowel stenoses 14 were classified as inflammatory and 5 as non-inflammatory. The leucocyte scan also showed 14 inflammatory stenoses. The not inflamed stenoses could not be diagnosed scintigraphically. The barium enemas of the small bowel and the leukocyte scans both correctly diagnosed the acute inflamed segments. The inability to show non-inflamed segments (n = 5) and to localise small bowel stenoses exactly is disadvantageous in the scan. The advantage of the leucocyte scan is a non-invasive examination without specific bowel preparation and the possibility to diagnose additionally inflamed large bowel segments (n = 4), fistulas and abscesses (n = 2). The leucocyte scan offers a useful expansion of the diagnostic tools in small bowel diseases, especially in radiological problems in patients with Crohn's disease.

Adult↗

[Possible causes of gas in the urinary tract].

During diagnostic procedures for various diseases, five patients underwent intravenous pyelograms which showed gas formations in the collector system, in absence of acute symptoms. Laboratory chemical, bacteriologic and radiologic examinations explained the origin of these gas formations. In one patient with diabetes mellitus and in another with an oesophageal neoplasm, infections were caused by gas forming bacteria. In three cases, bladder fistula formations were present by Crohn's disease, colon diverticulosis and a gynecological malignancy.

Adult↗

[Adenomyomatosis and cholesterol polyps of the gallbladder. A comparison of radiological and sonographic diagnosis].

To evaluate the accuracy of ultrasonic methods in diagnosing hyperplastic cholecystoses we performed sonography on 31 patients in whom adenomyomatosis of cholesterol polyps of the gall bladder had been diagnosed radiologically. Despite recent improvements in the image quality of ultrasound machines the ultrasonic method was no better in diagnosing cholesterol polyps than radiology and was inferior to radiology in diagnosing localized alterations of the gall bladder wall caused by adenomyomatosis. Thus for the latter radiology remains the method of choice.

Cholangiography↗

[Thickening of the gastric wall in the echographic section (author's transl)].

The distal portion of the normal stomach can now be visualized in the majority of patients undergoing echographic examination. Pathological thickening of the wall appear in the echographic section as a complete or incomplete cockade phenomenon. Besides the morphological appearance, abdominal echography also permits a certain assessment of gastric peristalsis and its disturbances frequently associated with the cockade phenomenon. With increasing size and rigidity of the wall, the complete cockade phenomenon suggests the presence of a malignant infiltration process in the wall; the incomplete pathological cockade phenomenon of the stomach is, on the other hand, far more ambiguous. Abdominal echography can consequently influence diagnosis directively and economically.

Humans↗

[Functional effects of micro-oil embolization following lymphography].

Lymphography, if performed correctly, has few clinically relevant complications. Nevertheless, the passage of oily contrast medium into the pulmonary vascular bed along physiological pathways can usually be verified radiographically and functionally. Since that part of the contrast medium filtered in the lungs is of no diagnostic value we think that a total amount of 14--16 ml Lipiodol Ultrafluid should normally suffice for outlining the retroperitoneal lymph passageways from the legs. With smaller amounts one may misinterpret an incomplete filling of the cranial paraaortic lymph nodes as filling defects. We agree with most authors that in patients with abnormal lung function, especially those with restrictive disorders, and in patients with pre-existing right heart strain lymphography should only be considered when truly indicated and only after testing of pulmonary function.

Contrast Media↗

[Angiographic studies in fluoroscopically detected coronary calcification (author's transl)].

We performed coronary angiography in eighty subjects with radiographically diagnosed coronary calcification. Radiographically proven coronary calcification is highly specific for coronary heart disease. Within certain limitations it helps in locating stenoses and is present more frequently in multiple vessel disease. It sometimes detects coronary artery disease missed by other non-invasive methods.

Adult↗