Biomedical subjects

M Jibu

Publications and source records attributed to M Jibu.

4 recordsLinked to original sources

PubMed2001

Theory of cell membrane organizers and pressure reversal of anesthesia.

A theory of pressure reversal of anesthesia is proposed from a modern framework of condensed matter physics. A highly ordered cooperative dynamics of ordered water in the perimembranous region of nerve cells is analyzed, and the emergence of a new phase of condensation of massive photons in the perimembranous region is derived theoretically. The critical temperature of the massive photon condensation is estimated to be higher than the body temperature. The anesthetic molecules break the order of the ordered water condensation, and decrease the critical temperature of the emergent massive photon condensation there - a possible mechanism of anesthesia. Condensed matter physics tells that the critical temperature of the condensation phase is proportional to the pressure. The critical temperature of the massive photon condensation once decreased by the anesthetic molecules increases under the high pressure, restoring the order of the massive photon condensation, thus suggesting the pressure reversal of anesthesia.

Anesthetics↗

PubMed1997

Evanescent (tunneling) photon and cellular "vision'.

The existence of a rudimentary form of cellular 'vision' was discovered experimentally by Albrecht-Buehler. He found that Swiss 3T3 cells approached distant infrared light spots and suggested that the most likely explanation for this phenomenon involves the long-range processing of electromagnetic signals by the cells. In this paper, a theoretical possibility of this phenomenon is presented within the fully quantum theoretical framework of the electromagnetic field and water. By taking into account the usually neglected interaction between the electric dipole field of water molecules and the quantized electromagnetic field, the dynamically ordered region of water surrounding the cell up to the coherence length < 50 microns is shown to play the role of a nonlinear coherent optical device through which the cells receive electromagnetic signals from distant light spots. The electromagnetic signals for the cell Albrecht-Buehler found are shown to consist of evanescent photons (i.e. soft polaritons) tunneling through the dynamically ordered region of water between the cell and the distant light spot. In contrast to the (normal) vision of animals realized by receiving (normal) photons, cellular "vision' is found to be realized by receiving evanescent photons. It is also suggested that the existence of the dynamically ordered region of water realizing a boson condensation of evanescent photons inside and outside the cell can be regarded as the definition of life.

3T3 Cells↗

PubMed1995

Excimer formation by hybridization using two pyrene-labeled oligonucleotide probes.

Pyrene excimer formation was achieved in an aqueous solution by nucleic acid hybridization. We used two different 16-mer oligonucleotide probes which had a combined continuous-sequence run complimentary to a target 32-mer. Prior to hybridization, the adjacent terminal ends (i.e., the 3'-terminal of one probe and the 5'-terminal of the other probe) were each labeled with one pyrene residue. The simultaneous hybridization of the probes to the target induced a 495-nm broad fluorescence band characteristic for pyrene excimer. Temperature and molecular configurations of the hybrid influenced the excimer formation.

Base Sequence↗

PubMed1994

Quantum optical coherence in cytoskeletal microtubules: implications for brain function.

'Laser-like,' long-range coherent quantum phenomena may occur biologically within cytoskeletal microtubules. This paper presents a theoretical prediction of the occurrence in biological media of the phenomena which we term 'superradiance' and 'self-induced transparency'. Interactions between the electric dipole field of water molecules confined within the hollow core of microtubules and the quantized electromagnetic radiation field are considered, and microtubules are theorized to play the roles of non-linear coherent optical devices. Superradiance is a specific quantum mechanical ordering phenomenon with characteristic times much shorter than those of thermal interaction. Consequently, optical signalling (and computation) in microtubules would be free from both thermal noise and loss. Superradiant optical computing in networks of microtubules and other cytoskeletal structures may provide a basis for biomolecular cognition and a substrate for consciousness.

Animals↗