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False Negative Reactions↗
Biomedical subjects
M Jiménez-Ayala
Publications and source records attributed to M Jiménez-Ayala.
Serous surface papillary carcinoma of the ovary metastatic to a cervical polyp. A case report.
BACKGROUND: Malignancies in cervical polyps are rare. In the literature, malignant transformation to adenocarcinoma and squamous cell carcinoma has been described, but metastasis from ovarian tumors has not been reported before. CASE: An asymptomatic female had a serous surface papillary carcinoma of the ovary, metastatic to a cervical polyp and first noticed on a routine vaginal/cervical/endocervical smear. CONCLUSION: The most common sources of adenocarcinoma cells in a cervical/vaginal smear are the endocervix and endometrium, but, as in our case, the tumor may well be metastatic disease, originating in the ovary or even in extragenital sites, such as gastrointestinal tract, breast and lung. The possibility of dual primaries, involving, for instance, both ovary and endocervix, should be considered.
Adenocarcinoma↗
The cytologic diagnosis of breast lesions.
In view of the increasing number of patients presenting with breast lesions, cytology was used as a first step diagnostic procedure. This is the first study of its kind in Spain. Material was obtained from 660 patients, either from spontaneous nipple secretion or by fine needle aspiration. Cytologic criteria for recognition of the different cell types in the smears are discussed. The accuracy of the method was high (2.6% false negatives; 4.1% false positives). The cytologic technique for diagnosing breast lesions is simple, rapid and economic as well as harmless and painless. It therefore fulfills all requirements for an early diagnostic procedure.
Breast↗
Endometrial and endocervical brushing techniques with a Medhosa cannula.
A new technique for obtaining endometrial material using the Medhosa Cannula is described. This method is also useful to obtain samples from the endocervix. The Medhosa Cannula is made of flexible plastic. It is 30 cm long and has thin fins on its distal end which, guided by an introduction cone, permit endometrial and endocervical brushing. Six hundred cases are reported. Concomitant histopathological studies were performed in 40 per cent of the patients. There were two false negative cytologic reports (0.88%) and one false positive (6.66%). This is a simple, rapid, innocuous and economical technique, thus fulfilling the prerequisites for routine cytodiagnostic methods. Adequate material was always obtained.
Adenocarcinoma↗
Hemangiopericytoma in a male breast. Report of a case with cytologic, histologic and immunochemical studies.
A hemangiopericytoma in a male breast was studied by fine needle aspiration (FNA) biopsy. The FNA smears contained tissue clumps showing knob-like formations of atypical cells, spindle-shaped cells and fragments of capillaries lined by normal endothelial cells. Immunocytochemical study showed a positive reaction for vimentin, but a negative reaction for desmin and keratin. Staining for Factor VIII was positive only in the capillaries and endothelial cells. The cytodiagnosis was "mesenchymal tumor." Histopathologic study of the mastectomy specimen made the final diagnosis of hemangiopericytoma. While FNA cytology and immunocytochemistry cannot make a definitive diagnosis of this rare vascular tumor, they can be decisive in planning the surgical treatment, as in the present case.
Adult↗