Biomedical subjects
Publications and source records attributed to M Jirina.
The authors demonstrate by comparing results of the mathematical model FMAR 8G and curves recorded during examination by means of a whole-body plethysmograph the influence of the expiration speed on value Rt in patients with an altered elasticity in the alveolar area and with an enhanced collapsibility of the respiratory pathways.
The authors present results of a comprehensive, mostly mathematical, solution of problems of the mechanism of breathing and ventilation. The need for a multivariant approach is based on the knowledge of disorders of the individual factors influencing ventilation. The authors are convinced that this approach means a useful contribution to the establishment of diagnosis and to economization of treatment.
In this work there are described two models of breathing mechanics which are aimed to the collapse problem of airways during expiration. The first model (FMAR 7) in the solution respects only the resistance problem of the airways walls against the ambient pressure. The second model (FMAR 8) takes account of the influence of elasticity of alveolar walls. The resultant curves were calculated according to the model (FMAR 8) on the parameter basis obtained by means of patient measuring and these are well comparable with curves noticed during the examinations of objective persons.
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Lung mass determination in cooperative subjects is possible by computation from the "flow-volume" loop, if total lung resistance (Raw) is known. The model is applicable to tracking changes in weightlessness. Modifications for improving the result are discussed.