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M Joshi

Publications and source records attributed to M Joshi.

97 records · Page 6Linked to original sources

Not all reading disabilities are alike.

In this article, reading disability is defined broadly to refer to below-average achievement in reading comprehension as assessed by a standardized test. With our research we tried to answer the question of whether all children with reading disability share a common etiology of deficient phonology, or constitute heterogeneous groups. The answer to this question was sought in four studies that examined reading disabilities from the perspective of componential skills of reading. In Part 1, the results of the first study are reported. A principal-components analysis of the performance of 139 children from Grades 3, 4, and 6 on reading-related tasks yielded two factors: decoding and comprehension. However, factor analyses conducted for each grade separately indicated that orthographic skill and processing speed could possibly constitute a third component. The orthography-speed factor emerged as a factor only in the 6th grade. Part 2 of this article reports the findings of three studies that analyzed the componential skills profiles of poor readers. It was found that the poor readers constituted heterogeneous groups and that four different types of poor readers could be identified with deficiency in any one of the following skills: (a) decoding only, (b) comprehension only, (c) a combination of decoding and comprehension, and (d) a combination of orthographic processing and reading speed. It was also found that the criteria used in selecting poor readers influenced the distribution of the ratio of the four types of poor readers within any given group.

Auditory Perception↗

Heat-induced changes in the photochemical centres and the protein secondary structures of photosystem II studied by variable fluorescence and difference FT-IR spectroscopy.

Variable fluorescence (Fv), i.e., Fv = Fm-Fo where Fo is the minimal fluorescence and Fm the maximum fluorescence, and difference Fourier transform infrared (FT-IR) spectroscopy were used to study the effect of heat stress in the 25-55 degrees C range on photosystem II (PSII) structure and function. First, the Fv intensity reflects accurately the changes in the number of open photochemical centers in PSII. Secondly, the use of Fv in combination with FT-IR spectroscopy can disclose structure-function correlations in the heat inactivation of the PSII complex. Analysis of the midpoint temperatures of thermal denaturation, i.e., 50% inactivation, reported so far in investigations of the thylakoid membrane components has revealed that most of the thermal transitions attributed to PSII are in the 39-46 degrees C range. In this work, it is shown specifically that the midpoint temperature of PSII inactivation is at about 40 degrees C. Moreover, it was clearly demonstrated that the heat-induced changes above 40 degrees C are the result of a marked decrease in the number of open photochemical centers in PSII. It was also seen that above this same temperature the loss of photochemical centers has its structural counterpart in overall modifications of the secondary structures of the PSII proteins resulting from the decrease in the alpha-helix content concomitant with the increase in extended chain (beta-strand) conformations. In brief, a novel finding reported here is that the number of open photochemical centers in PSII is dependent on a dynamic equilibrium between the contents of the PSII proteins in alpha-helix and extended chains (beta-strands), but not in beta-sheets and beta-turn structures except for the antiparallel-beta-sheet conformations. This therefore associates the thermal inactivation of the photochemical centers in photosystem II with distinct conformational changes in the proteins of the PSII supramolecular complex. In the particular context of the present study, these findings constitute a significant contribution to the investigation of structure-function correlations in the photosynthetic membrane. In a broader context, this information might be essential for the comprehension of the molecular arrangements or local structure order that are involved directly or indirectly in biological catalysis.

Pisum sativum↗