PubMed HealthSearch

Biomedical subjects

M Jungke

Publications and source records attributed to M Jungke.

5 recordsLinked to original sources

[Gadolinium dimeglumine gadopentetate compared to CPMG sequencing and image synthesis].

The skulls of 46 patients were examined by means of ordinary scans and after contrast. 24 of these patients with cerebral abnormalities had scans, using identical planes, with and without contrast and with CPMG sequences. Contrast in intracranial, but extracerebral (extra-axial), tumours (meningiomas, neurinomas) was much better after using contrast, but intracerebral (intra-axial) tumours were mostly shown as well on T2-rated CPMG sequences. Image synthesis has shown that contrast uptake occurred only in solid tumour regions.

Brain Diseases

[Initial clinical results of tissue characterization by T1, T2 and proton density in nuclear magnetic resonance tomography].

The NMR parameters (proton density, relaxation times T1 and T2) have been assessed by Carr-Purcell-Meiboom-Gill (CPMG) spin echo sequences. A computer assisted analysis of the data of 21 patients with cerebral tumours allowed a classification of tumour tissue in different tumours. The use of quantitative procedures for tissue characterisation allows the differentiation of benign and malignant brain tissue by characteristic colour coding demonstrating morphological details like tumour, edema and necrosis as well as indicating the histological types of the tumours of the central nervous system.

Brain

[Reference substance for initialling the marker space in NMR tomography].

Dimethylsiloxane polymers are tested to serve as a reference medium in quantitative MR imaging. Simultaneously measured during the patient's examination, the reference data are used to normalize the intrinsic MR tissue parameters. This method helps to achieve interindividual comparability of tissue vectors which are defined by proton density, spin-spin and spin-lattice relaxation times, thus leading to a remarkable improvement in tissue classification.

Brain

[Possibilities in using a specific pulse sequence (interlocking sequence) to improve the specificity in NMR tomography].

Methods and possibilities of application of a doubled and interlaced pulse sequence ("interlaced sequence") are discussed. This makes it possible to perform contrast variations and pulse sequence variations subsequently, as well as to determine the parameters proton density, T1 and T2. The selectivity of the combination of all three parameters for tissue classification is demonstrated by means of an individual case and seems to promise a higher specificity of MR tomography.

Brain Neoplasms

Information processing in nuclear magnetic resonance imaging.

An extended image analysis and classification system is presented to discuss the principal composition of the components as well as the methods of its realization in the field of reference based NMR diagnostics and tissue characterization.

Brain