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Biomedical subjects

M Jusić

Publications and source records attributed to M Jusić.

11 recordsLinked to original sources
PubMed1982

Nutritional status and physical working capacity.

In a population of schoolchildren aged 12-15 years in which biochemical deficiencies of vitamin C, riboflavin and pyridoxine affected 30.0, 33.9 and 17.2 per cent of subjects respectively, a small but statistically significant correlation was found between VO2max and vitamin C, riboflavin, vitamin A, and parameters of iron nutrition status. The administration of tablets containing 70.0 mg ascorbic acid, 2.0 mg riboflavin and 2.0 mg pyridoxine resulted in a statistically significant reduction in prevalence of vitamin deficiency, and in a small but statistically significant increase in VO2max. No such changes were observed in the untreated control groups. When data from both the experimental and control groups were pooled and analysed together, the results showed that the increase in VO2max was associated with an increase in plasma vitamin C level, in erythrocyte riboflavin content and in blood haemoglobin level. On the basis of presented data, it is not possible to conclude whether the increase in VO2max was the result of correction of vitamin deficiency per se or was due to its effect on resorption and utilization of dietary iron.

Adolescent↗
PubMed1980

Zinc nutrition and taste acuity in school children with impaired growth.

A study on the relationship between zinc nutrition status and the parameters of growth and physical development was carried out in a group of school children aged 9 to 12 years, selected from a population showing a higher prevalence of "below average" hair zinc concentrations. The growth of the children was assessed as the attained height for age in comparison with the reference population median, whereas the physical development was assessed on the basis of the weight for height and upper arm circumference. Taste acuity was also examined. The results showed an increased prevalence of the "below average" and "low" zinc values in hair and plasma in children of shorter stature and poorer nutrition status. The examination of taste acuity has shown that the occurrence of moderate to severe hypogeusia was statistically significantly associated with the reduction of hair zinc content. The children with moderate and more severe hypogeusia also belonged to the most poorly nourished in the examined population.

Anthropometry↗
PubMed1979

The effects of riboflavin administration on iron metabolism parameters in a school-going population.

The effect of riboflavin administration on iron metabolism was studied in a group of riboflavin-deficient children with Erythrocyte Glutathione Reductase (EC 1.6.4.2) reactivation above 1.20. The results have shown that the administration of riboflavin has resulted in a decrease of serum iron as well as in transferrin saturation which was accompanied by an increase in blood hemoglobin in subjects with initially lower hemoglobin values (less than or equal to 13.5 g/100 ml). There was, however, no change in blood hemoglobin in the group with initially higher hemoglobin values (greater than or equal to 14.0 g/100 ml). The results suggest that inadequate riboflavin intake may affect the iron utilization. The possible mechanism of riboflavin action on iron utilization is discussed.

Child↗
PubMed1976

Inactivation of yeast enzymes by proteinase A and B and carboxypeptidase Y from yeast.

Changes in the activities of 15 different enzymes during incubation of a crude yeast extract with the purified yeast proteinases A and B, and carboxypeptidase Y, respectively, have been measured. The spectrum of action of the three proteinases on the enzymes measured differs significantly, increasing or decreasing their activities or having no effect. Incubation of purified cytoplasmic malate dehydrogenase or purified mitochondrial malate dehydrogenase with proteinases A and B results in selective inactivation of the cytoplasmic enzyme, whereas the mitochondrial activity is not affected. Carboxypeptidase Y has no effect on the activity of either dehydrogenase. The results support the idea of selective proteolysis as the mechanism of the earlier observed inactivation of cytoplasmic malate dehydrogenase, initiated by the addition of glucose to intact yeast cells grown on acetate as carbon source ("glucose effect").

Carboxypeptidases↗