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Biomedical subjects

M K Chu

Publications and source records attributed to M K Chu.

3 recordsLinked to original sources

Moyamoya disease initially presenting visual field defect.

Progressive narrowing of distal carotid arteries and the development of compensatory fine networks are the characteristic findings of moyamoya disease. Cerebral infarction in moyamoya disease is due to a decreased blood flow and shows an uneven distribution in the distal bed of the anterior and middle cerebral arteries. The progression of disease in the posterior circulation follows that in the anterior circulation. Posterior circulation symptoms due to cerebral infarction usually occur in the advanced stage of the disease and follow the anterior circulation symptoms. We encountered an unusual case of moyamoya disease which initially presented with a transient visual field defect. One month later our patient developed blindness and her cerebral angiography showed advanced moyamoya disease.

Adult↗

Single-layer continuous anastomosis in gastrointestinal surgery: a prospective audit.

BACKGROUND: Single-layer intestinal anastomoses have been constructed conventionally using an interrupted suture technique. It is however, increasingly popular to perform such anastomosis using a continuous suture. METHODS: One hundred and eighty consecutive patients with 254 continuous single-layer anastomoses performed over a 4 year period were included in the study. Sixty-one patients underwent oesophagectomy, oesophageal bypass or gastrectomy, 32 underwent biliary bypass, hepatic, biliary or pancreatic resection and 88 had colorectal operations. The median age was 67 years. RESULTS: There were 254 anastomoses of which four leaked (1.6%). Fifteen patients (8.3%) died in hospital. CONCLUSION: These results show that the single-layer continuous suture technique is safe in gastrointestinal anastomoses.

Adult↗

Blood coagulation monitoring and anticoagulant therapy after liver resection: brief report.

In this sample of 140 patients undergoing hepatic resection to remove cancerous tissue, hypercoagulation was the most common postoperative BCD; in ten patients, this complication led to hepatic failure and hepatic coma. These findings differ from those previously reported in the literature, possibly because our patients had advanced hepatomas which had already infiltrated the great vessels of the liver, and/or the remaining liver was seriously cirrhotic. We found that blood-coagulation monitoring and anticoagulation therapy yielded encouraging results, and it is our hope that this treatment in combination with immunotherapy will prolong the survival of these patients.

Adolescent↗