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Biomedical subjects

M K Roberts

Publications and source records attributed to M K Roberts.

5 recordsLinked to original sources

Whipple's disease involving the pericardium: Pathological confirmation during life.

Cardiac involvement in Whipple's disease has been a frequent autopsy finding but is rarely recognized clinically. We report here a patient, a 63-year-old man, in whom Whipple's disease was diagnosed in 1974, based on a seven-year history of arthralgia, one-year history of weight loss and steatorrhea, and diagnostic small bowel biopsy. Despite complete regression of all joint and bowel symptoms following a prolonged course of tetracycline therapy, the patient developed incapacitating congestive heart failure and signs of constrictive pericarditis, for which a thoracotomy and pericardectomy was performed. Histologic examination revealed fibrous pericarditis with mononuclear infiltrates, including PAS-positive histiocytes. The characteristic bacilliform bodies were identified by electron microscopy in the resected pericardium. This to our knowledge is the first such demonstration during life of Whipple's disease involving the heart.

Humans

Assortative mating by unwed biological parents of adopted children.

Analyses of data obtained from 662 unwed couples whose children were relinquished for adoption reveal that biological parents of adopted children mate assortatively. For physical characters, assortative mating of unwed parents was similar to that of wed parents; for behavior characters, however, there was less assortative mating by the unwed parents. Because assortative mating inflates estimates of genetic parameters in adoption studies, future studies should collect information on both biological parents.

Adoption

Fluid resuscitation in the adult trauma patient.

Successful fluid resuscitation of the trauma patient requires prompt assessment and initiation of fluid therapy. This article discusses the fluids and blood components that may be used in the resuscitation period for the adult trauma patient, as well as potential complications of fluid resuscitation therapy and nursing interventions.

Education, Nursing, Continuing