Biochemical composition of different regions of the brain in malnourished children.
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Biomedical subjects
Publications and source records attributed to M K Sarma.
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Isotonic conditions for the integrity of subcellular organelles are shown to be remarkably influenced by the concentration of sucrose present during their isolation by centrifugation. Using the technique of enzyme osmometry, we show that the content of sucrose in synaptosomes reflects nearly total equilibration across the membrane during centrifugation, due to altered permeability of membranes. Presence of sucrose in the matrix space of mitochondria, as demonstrated by enzyme osmometry of matrix enzymes, indicates that the sucrose-space hypothesis is invalid.
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