Biomedical subjects

M Kabelková

Publications and source records attributed to M Kabelková.

3 recordsLinked to original sources

PubMed2002

Infective endocarditis caused by unusual gram-positive pathogens.

Of a total of 81 patients hospitalized in the infectious diseases department in 1990-2000 with infectious endocarditis caused by Gram-positive pathogen, unusual etiological agents were found in several cases: Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, and Gemella morbillorum. Cardiac defects were present in the latter two patients: bicuspid aortic valve and tetralogy of Fallot. Two patients were successfully treated with antibiotics only and one patient with antibiotics and surgery. The patient with C. diphtheriae endocarditis died due to progressive sepsis and multiple organ failure.

Adult↗

PubMed1997

[Clinical experience with Timentin].

BACKGROUND: A combination of ticarcillin with clavulanate has been used for more than 12 years in many countries in the treatment of infections caused by Gram-negative microorganisms and a mixed microbe flora, in particular where the presence of beta-lactamase producers can be anticipated. In the Czech Republic it is not very well known, probably more for commercial than medical reasons, and the objective of the present paper to draw attention to this old but still useful antibiotic. METHODS AND RESULTS: In a simple open trial the therapeutic results in a group of 15 patients treated by the above preparation in 1992-1995 at the unit for septic infections of the Clinic for Infectious Diseases in Prague were summarized and compared with the results of a previous trial conducted in the same department in 1987-91 and with results published in the literature. The mean success of treatment was about 90%. CONCLUSIONS: A combination of ticarcillin, a semisynthetic broad spectrum penicillin with clavulanic acid is an antibiotic which is still very valuable in the treatment of sepsis and other severe forms of bacterial infection, incl. patients with a significantly reduced immunity. The tolerance is very good and an important factor is also the relatively favourable price. The author's results are consistent with experience published by departments abroad.

Adult↗

PubMed1996

[Comparison of various methods of hemoculture tests].

Three methods of blood cultivation were compared: collection of blood into transport bottles containing only dextran-sulphate, collection into cultivation media containing bottles (aerobic, anaerobic and paediatric Dulab) and the semi-automatic continuous blood culture system (Bactec 9000, using aerobic, anaerobic and paediatric bottles). A total amount of 1.250 blood samples collected from 626 patients was divided equally into the compared bottles and processed parallelly. The yield of the Bactec aerobic bottles was significantly higher than the yield of the transport bottles and aerobic Dulab bottles (p < 0.001). However, this result was influenced by the higher rate of contaminating bacteria isolated from the aerobic Bactec bottles. The yield of the aerobic Dulab bottles was higher than the yield of the transport bottles (p < 0.01). The average time needed for the detection of microorganisms in the Bactec bottles was by 24 hours shorter than in the transport bottles and by 19 hours shorter than in the aerobic Dulab bottles (p < 0.001). The difference between the yields of the anaerobic and the paediatric bottles in our study was not significant. The time needed for the detection of microorganisms was by 17 hours shorter in the anaerobic Bactec bottles than in the transport bottles (p < 0.05).

Bacteria↗