Biomedical subjects

M Karnell

Publications and source records attributed to M Karnell.

3 recordsLinked to original sources

PubMed2001

Vocal process granuloma.

BACKGROUND: This review article reports the evolution of knowledge regarding the benign proliferations of the posterior glottis commonly termed "vocal process granuloma". METHODS: A comprehensive review of publications addressing lesions of the posterior glottis is affected to analyze the contemporary management of vocal process granuloma. RESULTS: Contemporary management emphasizes interventions to decrease irritation to the posterior glottis. Multiple causes of this irritation preclude use of a single management plan that will successfully address all cases. CONCLUSIONS: Management to diminish laryngopharyngeal reflux, as well as to correct vocally abusive behavior, will appropriately address the majority of vocal process granuloma. Surgical removal is best reserved for cases when conservative management fails, when airway obstruction is a concern, or when a biopsy is needed to establish the diagnosis. Ancillary measures that may be beneficial in specific cases include the use of steroids, antibiotics, membranous vocal fold augmentation, and laryngeal botulinum neurotoxin injection.

Glottis↗

PubMed1998

Allergy for the laryngologist.

Allergic disease can affect any portion of the respiratory tract, including the larynx, trachea, bronchial tree, nasal cavity, paranasal sinuses, nasopharynx, and pharynx. This review evaluates laryngeal manifestations of allergic disease and the impact of allergic mechanisms in disorders, within the scope of laryngology.

Anti-Allergic Agents↗

PubMed1989

Transoral carbon dioxide laser ablation for cancer, tumors, and other diseases.

A carbon dioxide laser was used on 71 patients for the removal of oral cavity or oropharyngeal cancers, premalignant lesions, benign tumors, or elongated soft palates. Evaluation of patient morbidity, speech, and swallowing, as well as survival data, suggests that the use of this modality for treatment of these conditions is highly successful, with excellent preservation of oral and pharyngeal function and minimal patient morbidity. Deep excisions of tumors that could lead to restricted motion of the tongue and/or jaw tended to have an adverse effect on both speech and swallowing. Immediate reconstruction should be considered, especially for defects created by excision of large tumors in the anterior oral cavity or in the lateral oropharyngeal wall cancers. Multimodality cancer therapy should be considered for large oral cavity and oropharyngeal cancers that have been treated by carbon dioxide laser excision.

Adolescent↗