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M Kasuya

Publications and source records attributed to M Kasuya.

76 records · Page 5Linked to original sources
PubMedDate not supplied

Elemental concentrations in hair of inhabitants of a cadmium-polluted area.

To investigate the present situation of inhabitants living in the cadmium-polluted area of Toyama Prefecture, 95 hair samples were analyzed instrumentally by the neutron activation method. The concentrations were compared with nonpolluted samples. The concentrations of Cd, Cu, Zn, and Cu/Zn in hair were compared with those in some reported organs. The values of Cu/Zn were significantly lower (p less than 0.001) in hair of both female groups, but only somewhat lower (p less than 0.05) in hair of the male group. Causes of these facts are discussed. Results obtained from principal component analysis are also mentioned.

Adolescent↗
PubMedDate not supplied

Cross-sectional assessment of renal function in the inhabitants of a cadmium-polluted area.

To understand the development of cadmium (Cd)-induced renal tubular dysfunction, cross-sectional assessment of renal function in the inhabitants of the Cd-polluted Jinzu River basin in Toyama, Japan, was carried out. Sixty-seven men and 78 women, aged 56 to 71 years whose urinary beta 2-microglobulin (beta 2-m) exceeded 1,000 micrograms/g creatinine, were examined and divided into five groups according to their values of fractional excretion of beta 2-m (FE beta 2-m). Comparisons were made between six groups including the inhabitants of a non-polluted area as a reference group. Significantly increased values of fractional excretion of urate (FEUA), calcium (FECa), sodium (FENa), and chloride (FECl), serum creatinine and beta 2-m, and urinary protein were detected even in the subjects with FE beta 2-m level below 1 percent compared with the reference group. Fractional phosphate reabsorption (percent TRP) was significantly decreased in the subjects with FE beta 2-m level above 10 percent. Creatinine clearance (CCr) decreased with increase in FE beta 2-m, and the subjects with FE beta 2-m above 30 percent showed significantly decreased CCr values compared to those with FE beta 2-m below 30 percent. In summary, FEUA, FECa, FENa, and FECl, as well as low-molecular-weight proteins such as beta 2-m, are increased in the early stage of Cd-induced renal tubular dysfunction. Although percent TRP was maintained by the decreased CCr, there was a marked decrease in percent TRP in subjects with progressive stage showing FE beta 2-m level above 10 percent. No sex difference in renal tubular dysfunction was found in this cross-sectional study.

Aged↗