[The occurence of hyperlipoproteinemia (according to Fredrickson's classification) in the early and the late period of myocardial infarction (author's transl)].
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Biomedical subjects
Publications and source records attributed to M Kedra.
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In blood serum of healthy persons the activity of arginase (EC 3.5.3.1) is very low, whereas in patients with myocardial infarction it increases within a few hours after the first attack of coronary pain, and returns to normal values after 3-5 days. No increase of arginase activity was observed in sera of patients with angina pectoris, coronary insufficiency or cardiac failure. Determination of arginase activity in blood serum may serve as a useful test in early differential diagnosis of myocardial infarction.
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The purpose of the study was to assess the frequency of infarction of the posterior wall of the left ventricle which shows a high R wave in leads V1-2 on electrocardiogram. Serial electrocardiograms of 1 452 patients with myocardial infarction were analyzed. Features of posterior wall infarction were found in 106 cases (7.3%). In 13 cases, the area of infarction was limited to the posterior wall; in 12 cases, concomitant features of lateral wall infarction were found; in 38 cases, the changes involved the inferior wall as well, and in 43 cases, the inferior and lateral walls were involved concomitantly. A high R wave in V1-2 was observed already in the first ECG obtained on the day of the onset of the disease in 32 out of 106 cases, while in 74 cases it appeared only in the subsequent days. High voltage of R wave was found in V1 exclusively in 20 cases, in V2 exclusively in 36 cases, and simultaneously in V1 and V2 in 50 cases. The analysis suggests that posterior wall infarction is fairly frequent (7.3%) but occurs in only 1% of cases as an isolated process. Knowledge of the features of posterior wall infarction is of practical importance; simultaneous detection of features of infarction of the posterior and the inferior or lateral walls is proof of a widespread myocardial necrosis and may be of prognostic significance.
Hospital rehabilitation of patients with myocardial infarction was conducted according to the model worked out by the Institute of Cardiology in Warsaw and modified at the Department of Cardiology of the Medical Academy in Lublin. According to their clinical condition, the patients were divided into 3 groups. Group A comprised patients with extensive myocardial infarction and complications; duration of hospital stay was 28 days. Group B included patients with extensive infarction without complications; hospital stay was 21 days. Group C included patients with limited myocardial necrosis and a mild course of the disease, and duration of stay of 14 days. Out of 1000 patients with myocardial infarction 134 (13.4%) died within the first 4 days after admission, i.e. before the beginning of rehabilitation treatment; 56 (5.6%) died during rehabilitation. The group of patients undergoing rehabilitation treatment comprised 866 patients (86.6%), including 382 (44.1%) in group A, 404 (46.6%) In group B, and 80 (9.3%) in group C. The mean duration of hospital stay of all patients with myocardial infarction was 24.3 days; in 80 cases (9.9%) it was 14 days, in 397 cases (49.0%) 21 days, and in 236 cases (29.1%) 28 days. In 97 cases (12.0%) hospitalization was longer than 28 days. Work was resumed by 30% of white and blue collar workers and 89.5% or farmers within the productive age groups.
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