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Biomedical subjects

M Kelle

Publications and source records attributed to M Kelle.

2 recordsLinked to original sources

[Intussusception in adults].

The authors report eight cases of intussusception of small and large intestine in adults during five years. 3 of the intussusception caused by simple tumors in five cases by malignant. In three cases were chronic presented long term signs and symptoms. Ileo-ileal invagination was diagnostised at 3 patients, ileo-caecal in one case and ileocolic intussusception also in one case. In 2 cases developed caeco-colic, in one case colo-colic invagination. Resection was strongly indicated in seven cases and wedge resection was done at the last patient. One patient has died of cerebral multiple embilization. They review the etiology and pathology, the signs and symptoms as well as the difficulties during diagnosis and treatment of the intussusceptions according to their own experience and literary datas. The authors draw the attention to the importance of the modern iconographic, tools, particularly the ultrasonography in the diagnosis of intussusception.

Adolescent↗

[Successful treatment of hepatocellular carcinoma with All-trans-retinoic acid].

A 44-year-old female patient was admitted to our department with diagnosis of malignant lymphoma. The abdominal USG and CT showed multiple liver lesions with partial portal vein thrombosis, moderately increased alfa-fetoprotein (AFP), ASAT, ALAT (2x normal value), serology was negative for HBV and HCV. Liver transplantation was suggested but refused because of portal vein thrombosis. ATRA (45 mg/m2/day orally) was given on the basis of the assumption that HCC and acute promyelocytic leukaemia share similar oncogenic pathway (alter the RAR alpha and beta receptors). She was gained 15 kg-s and has resumed her work as a teacher for the last 20 months. Abdominal CT showed a complete regression of the intrahepatic tumour.

Adult↗