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Biomedical subjects

M Kinirons

Publications and source records attributed to M Kinirons.

At least 19 recordsLinked to original sources

Dental caries experience of children with haemophilia in Northern Ireland.

It is generally agreed that persons suffering from haemophilia from a priority group for dental care. The present study compares the prevalence of dental caries in haemophilic children in Northern Ireland with the reported values for similarly aged children in the population. The prevalence of caries experience and of untreated caries were low in the haemophiliacs in both the primary and permanent dentitions. No teeth had been extracted due to caries and a high level of fluoride usage was claimed. The dental care of these patients is carried out at the regional treatment centre and forms an integral part of their medical care.

Adolescent

A survey of factors influencing the prescribing of sugar-free medicines for children by a group of general medical practitioners in Northern Ireland.

Factors which influence the prescribing of sugar-free medicines by 47 general medical practitioners were examined by means of questionnaire. The doctors all practise in the Newry and Mourne district of the Southern Health and Social Services Board, Northern Ireland. Twenty-six (55%) of the doctors stated that they support the principle of prescribing sugar-free medicines for children; the same number stated that they oblige parental requests and 14 (30%) stated that they frequently prescribe a common group of sugar-free medicines. However, only 14 (30%) of the doctors considered that their knowledge of sugar-free medicines was up-to-date. The main sources of information about sugar-free preparations were drug company travelling representatives and professional journals, but a few doctors learned of this issue from other professionals, including dental practitioners. The majority of doctors (especially those with a practice policy of prescribing sugar-free medicines) felt it was important to prescribe sugar-free preparations for all children, not only for those requiring long-term medication. The results show that there is a reasonable level of interest in this issue among the doctors in the area, but that there is an on-going need for further encouragement and provision of information for them, in order to increase as far as possible the use of sugar-free preparations for children.

Adolescent

Familial and maternal factors affecting the dental health and dental attendance of preschool children.

Factors affecting the dental health and dental registration of preschool children were examined. Questionnaires were completed for 340 randomly selected children and the dental caries status of 294 of these children was examined. There was a statistically significant relationship between the dental caries experience of the child and its position in the family, the lowest caries experience occurring in the second and third born. The peak age of new dental registration appeared to occur during children's third year. The person responsible for bringing the child for dental appointments was the mother in 290 instances out of 340. Maternal education level was significantly associated with child dental health. The caries prevalence in children whose mothers were educated to 3rd level was 10.6 per cent as compared to 38.1 per cent for 2nd level and 46.8 per cent for below '0' level mothers. Mothers who were relaxed about their own dental care were the most likely to have preschool children who were registered for dental care. Similarly those mothers whose last dental visit occurred in the previous six months were the most likely to have children who were registered.

Adult

Occupational stress factors in hospital dentists.

This investigation examined perceived stress levels, personality characteristics and stress outcomes in a group of hospital dentists working in Belfast. Mean scores for this group were also compared with normative values. The occupational stress indicator was distributed to 45 hospital dentists; 40 returned the completed questionnaire. The mean score for each stress-related factor was analysed and compared with normative values. In addition the ranked scores for sources of stress were examined, and no significant differences could be demonstrated between the two groups. However, for external locus of control this group of hospital dentists demonstrated a significantly higher mean score of 42.3 than the mean normative value of 38.6. The dentists' score for their perception of their state of physical ill health was 23.9 and was significantly lower than the normative value of 27.8 but no differences could be demonstrated between the groups for mental health, Type A personality or mean stress levels.

Administrative Personnel

Familial adult medullary cystic disease with spastic quadriparesis: a new disease association.

We present two cases of familial adult medullary cystic disease with spastic quadriparesis, an association not previously described. Previous extrarenal associations of the nephronophthisis-medullary cystic disease complex were reported exclusively in childhood cases. Both patients have undergone successful cadaveric renal transplantation, with no evidence of their renal disease recurring. Further work is needed to elucidate the complex genetics of nephronophthisis.

Abnormalities, Multiple

Heart rate and metabolic response to competitive squash in veteran players: identification of risk factors for sudden cardiac death.

We studied 10 older males during a competitive game and the early post-exercise period to define the metabolic response to squash in veteran players. For comparison, all subjects were also studied during exhaustive treadmill exercise. Squash caused a dramatic increase in heart rate (150%), and circulating levels of noradrenaline (164%), adrenaline (93%), lactate (202%) and free fatty acids (67%). These effects were independent of haemoconcentration. The early post-exercise period (5 min) was characterized by persistent elevation of plasma catecholamines, lactate, and free fatty acids, hypokalaemia and ventricular arrhythmias. The heart rate and metabolic responses to squash were similar in pattern and magnitude to those observed during treadmill exercise, highlighting the strenuous nature of squash as a recreation sport. While these changes may represent appropriate physiological adaptation to exercise in health, each has been implicated in the pathogenesis of fatal ventricular arrhythmias in subjects with ischaemic heart disease. These data support the contention that squash may be an inappropriate form of exercise for older men with coronary artery disease.

Arrhythmias, Cardiac

Clinical findings in 12 patients with MPS IV A (Morquio's disease). Further evidence for heterogeneity. Part II: Dental findings.

Typical dental changes were present in all cases, although they were of variable degree. However, the tooth morphology would appear to be highly specific for MPS IV A, and is not found in MPS IV B (beta-galactosidase deficiency) or the recently delineated MPS IV C (enzyme defect unknown). Thus the dental changes have a very useful diagnostic potential in mild atypical cases of MPS IV A, although they may only be demonstrable radiologically in some such cases.

Adolescent

Cardiopulmonary resuscitation: doctors and nurses expect too much.

Doctors and nurses in the UK and US have an over-optimistic view of patients' chances of surviving an attempt at cardiopulmonary resuscitation (CPR). If medical staff are to follow the recommendation that they should discuss the pros and cons of CPR with patients and their relatives, they should at least be able to give them realistic expectations of survival; otherwise inappropriate decisions may be made. Resuscitation training programmes should routinely include data on survival from CPR in differing circumstances.

Cardiopulmonary Resuscitation

Does audit improve DNR decision making?

The use of 'do not resuscitate' (DNR) orders in hospitals has been the subject of considerable comment in both the medical and the lay press. Guidelines have been produced to help make DNR decisions but, as yet, there have been no published accounts of these in practice. We have used audit to accounts of these in practice. We have used audit to develop DNR policy in our hospital, and have reviewed practice after the introduction of guidelines. This led to early consultant involvement in making decisions in 55 of 80 patients (69%) who were assessed as DNR at the time of death or discharge, documentation of reasons for DNR in all 55 of these and documentation of discussion with nurses in 49 (89%). Consultants agreed with DNR decisions made by their juniors in 31 of 34 cases (91%) and changed 'for CPR' decisions to DNR in 24 of 108 (22%). We have demonstrated that audit is an appropriate way to change and develop practice in sensitive areas such as this.

Adolescent