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Biomedical subjects

M Kirchgessner

Publications and source records attributed to M Kirchgessner.

At least 253 records · Page 14Linked to original sources
PubMed1980

[Energy balance study with a carbohydrate-free protein-fat diet].

The effect of a carbohydrate-free protein-fat (PF) diet compared with a mixed diet (CPF diet) on the energy metabolism was studied in a changeover trial with mature sows. The PF diet contained two thirds of its metabolizable energy as protein and one third as fat; in the CPF diet the relationship was 3.5 carbohydrate: 1 protein: 0.2 fat. Under the conditions of undernutrition and neutral temperature nitrogen, carbon and energy balance were assessed as parameters according to the procedures of indirect calorimetry in four 24-hour measurements each for the gaseous exchange of the animals. At isocaloric supply of metabolizable energy, no differences were found in the N, C and energy retention. The mean heat production amounted to 23.6 MJ/day in both dietary groups. Also, no dietary influence could be observed with regards to the daily time pattern of heat production nor to the physical activity of the animals. Computation of the nutrient utilization on the basis of potential ATP formation resulted in a turnover of 304 mol ATP/day for the mixed diet and in 275 mol ATP for the carbohydrate-free diet. The discrepancy is discussed. Overall, the results show that an increased heat production, providing the possibility of an augmented loss of body energy, could not be induced by the carbohydrate-free protein-fat diet in the course of undernutrition.

Adenosine Triphosphate↗
PubMed1979

[Utilization of alimentary ribonucleic acid in calf N-metabolism].

In order to get hints concerning the utilisation of nucleic acids in the N-metabolism of ruminants, a N-balance experiment with not yet ruminating calves was carried out. An admixture of 0, 1.875 and 3.75% yeast ribonucleic acid (groups I-III) was given to a milk substitute feed with low purine and pyrimidine contents. The RNA admixture amounted to 10 resp. 20% of the diet protein-N. The daily feed per animal amounted to 1710 g. Apart from the N-balance the digestibility of RNA and some N-fractions in urine were registered. The excretion of nitrogen, RNA or desoxy ribonucleic acid in the feces of the calves was hardly changed by the RNA intake. Thus an extensive digestibility of RNA can be stated. The renale nitrogen excretion increased in group II by an amount which nearly corresponded to the RNA intake, and in group III it even increased overproportionally. As the N-balance showed, there was a low utilisation of the RNA-N of 12% (non-significant), whereas in group III the N-increase was negatively influenced. The N-excretion in urine connected with the RNA-intake could mainly be traced back to increased urea and allantoine values. The conclusions from these results were that nucleic acids of 10 to 20% of the feed protein are only of a low resp. no nutritive nitrogen value.

Animals↗
PubMed1979

[Activity of proteases, leucine arylamidase and alpha-amylase in pancreatic tissue during nickel deficiency].

In studies on the essentiality of nickel, important differences of enzyme activities and also of substrates were established. The results of the present paper show that these changes cannot be explained by a lowered reduction of dietary proteins, since the activity of the proteases rather increased during Ni deficiency. However, the digestion of the starch by alpha-amylase, being 57% lower, could have been partially responsible for the large differences in the activities of the hepatic enzymes and in the concentrations of the hepatic metabolites and also in the weight gains.

Aminopeptidases↗