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Biomedical subjects

M Klar

Publications and source records attributed to M Klar.

8 recordsLinked to original sources
PubMed1991

Aseptic loosening of straight- and curved-stem Müller femoral prostheses.

Out of 1099 Müller total hip prostheses with straight and curved stems consecutively implanted between 1980 and 1984, those performed in as homogeneous a group as possible of patients under the age of 70 years were selected for the present retrospective study. There were 158 straight femoral stems with cementless RM acetabular cups, 105 straight stems with cemented Müller acetabular cups, and 158 curved stems with cemented Müller acetabular cups, and their results over a mean follow-up period of 5.8 +/- 1.24 years were compared. Six (3.7%) curved and 5 (1.9%) straight-stem prostheses were exchanged due to aseptic loosening; 26 (16.3%) curved and 54 (20.1%) straight-stem prostheses were "at risk" or loose at the time of follow-up. Survival curves show a worse result for straight stems after 6 years; within a follow-up period of 6-8 years there was significantly more radiological loosening in straight stems than in curved. Loosening in straight stems is assumed to develop mainly as a physiological reaction to the presence of bone cement particles.

Aged↗
PubMed1989

Association of class I, II, and III MHC gene products with systemic lupus erythematosus. Results of a Central European multicenter study.

Class I, II, and III MHC gene products were examined in 248 Central European SLE patients. The previously reported association with HLA-A1, -B8 and -DR3, and C4AQ0 alleles was confirmed. The frequency of HLA-DR2 was also slightly elevated in SLE patients, while no increase in C4BQ0 alleles was observed. Additional findings were a significantly increased frequency of HLA-B13 and a significant decrease of HLA-B44.

Alleles↗
PubMed1979

[Objectivation of tremor and motion disorders via computerisation (author's transl)].

The quantitative analysis of motion disorders of the upper extremities can be performed by means of a joystick connected with a minicomputer. Therefore a random squarewave curve is drawn on a computer display and the patient must follow it with the joystick. The deviation of the two curves are recorded, analysed and documented numerically and graphically.

Diagnosis, Computer-Assisted↗
PubMed1978

Computer-assisted stereotactic brain operations by means including computerized axial tomography.

With a computerized program system for stereotactic brain operations it becomes possible for the first time to react even before running a possible risk, e.g., in case of punctures in the midbrain, the brain stem, or in the hypothalamus, by simulating the operative procedure even before starting the operation itself. This is effected by the ability to change the penetration angle of the electrode or by choosing a different point of trepanation. The inclusion of computerized axial tomography, especially through the presentation of the CT scan, made to measure with the help of the linear transformation, and of the input of the cranial and ventricular coordinates through a digitizer, together with the coordinates resulting from the X-ray picture, brings the definition of the target point to a still greater optimum. Thus the safety and the precision of the stereotactic operation have been improved even further.

Brain↗
PubMed1977

A computer programme system for stereotactic neurosurgery.

A computer programme system is reported which allows a simulation of a stereotactic operation. It incorporates the determination of intracerebral structures and the electrode tract by means of boney reference points as well as the calculation of the parameters for the stereotactic apparatus. It contains further a library of brain sections, by which the electrode tract within the target structures can be shown on a computer display.

Computers↗
PubMed1977

[An information retrieval system for CT-scan data (author's transl)].

A computer program for the current statistical documentation and evaluation of CT diagnostic results is presented. A diagnostic key for the purposes of CT results has been developed. Special emphasis has been given to fast and simple applicability.

Central Nervous System Diseases↗