Biomedical subjects

M Klitzke

Publications and source records attributed to M Klitzke.

5 recordsLinked to original sources

PubMed1995

Case study: sleep and aggressive behavior in a blind, retarded adolescent. A concomitant schedule disorder?

Blind people are prone to suffer from sleep-wake schedule disorders. This report describes 2 months of monitoring of sleep patterns and aggressive behaviors in a totally blind, severely retarded adolescent boy, hospitalized in a psychiatric hospital. The documented sleep-wake patterns seem to portray a sleep-wake schedule disorder with a monthly periodicity. Aggressive behaviors seem to echo the same periodicity, suggesting that a common or linked biobehavioral timing mechanism may underlie both sleep and episodic aggressive outbursts. The need to consider sleep schedule disorders as a primary process underlying some psychopathological disorders, and the related risks of misdiagnosis and mistreatment, are highlighted.

Adolescent↗

PubMed1994

Dementia of adult polyglucosan body disease. Evidence of cortical and subcortical dysfunction.

OBJECTIVES: To characterize the dementia associated with adult polyglucosan body disease (APBD) and to correlate the cognitive deficits with abnormalities found on magnetic resonance imaging (MRI). METHODS: Quantitative neuropsychological testing and MRI in one man with APBD and a review of the literature. RESULTS: The dementia of APBD affects cortical and subcortical functions. The cognitive deficits correlate with MRI findings of cortical atrophy and white-matter abnormalities. CONCLUSION: Neuropsychological testing and MRI are helpful in the evaluation of patients with APBD.

Brain Diseases↗

PubMed1991

Role reversal and the self-effacing solution: observations from infant-parent psychotherapy.

In our culture, it is widely accepted that one of the central tasks of parenting is the promotion of psychological autonomy in one's children. For parents who have achieved a reasonable measure of psychological autonomy themselves, a flexible response to the child's dual needs for dependence and independence will support the child's need for nurturance without thwarting strivings for independent mastery. In other cases, this balance is not achieved. This paper describes a particular form of relationship disorder between parents and infants in which the major theme of the relationship is an intense and unrelenting interdependence. Parent and child are inextricably bound by a shared belief that each is essential to the other's psychological well-being. The disordered relationship is characterized by mutual anger, disappointment, and/or anxiety that makes the intense closeness mutually dissatisfying. These relationships no doubt exist on a continuum, but at the clinical extreme, which is our focus, they are conflict-ridden and painful for both parent and child.

Adult↗

PubMed1990

Self-monitored smoking motives.

The motives for smoking in 73 low, medium, and high rate smokers were surveyed and were evaluated the validity of the Reasons for Smoking scale (RFS) by correlating RFS scores with self-monitored reasons for smoking. Combined sample correlations were significant for 5 of the 6 RFS reasons. However, all correlations were modest, the number of correlations varied with smoking rate, and the RFS was not a valid measure of pleasurable relaxation, the reason most frequently reported during self-monitoring. The unexpected finding that pleasurable relaxation, not reduction of negative affect, was the most frequently endorsed reason conflicts with previous surveys, almost all of which sampled older smokers. Smoking behavior of younger smokers may differ from older smokers in ways important to the study of smoking motivation. These differences may explain why experimental studies with undergraduates generally find no relationship between smoking and negative affect while studies with older subjects do.

Adolescent↗

PubMed1979

[Effect of lead and carbon monoxide under the condition of diabetic metabolism (author's transl)].

The NZO-Mice were used to study the influence of carbon monoxide and lead under the condition of diabetic metabolism. The animals treated with 80 ppm (COHb 10.81) showed significantly lower tolerance for glucose. Even after removing the burden of carbon monoxide for 50 days, the blood sugar level after glucose tolerance test remained in experimental animals significantly higher than in controls (20-min-value). The NZO-Mice after enteral lead exposition showed no significant changes of the condition of the diabetic metabolism after the glucose tolerance test. However, the NZO-Mice, compared to NMRI mice and rats, reached significantly higher level of blood sugar.

Animals↗