Biomedical subjects

M Kontek

Publications and source records attributed to M Kontek.

At least 19 recordsLinked to original sources

PubMed1992

[Confirmed and borderline hypertension found in 44% of men (aged 40-59 years) working at the H. Cegielski plant in Poznań].

Blood pressure was measured in 3317 men, aged 40-59, working in H. Cegielski Metal Works in Poznań. The average systolic pressure for the whole population was 130.9 mmHg (SE = 17.90). The average diastolic pressure was 83.7 mmHg (SE = 10.03). The systolic, diastolic and mixed systolic-diastolic hypertension was found in 539 men which makes 16.3% of the study group. The borderline systolic hypertension was found in 327 men i.e. 9.9%, borderline diastolic hypertension in 267 men i.e. 8.0%. Both systolic and diastolic borderline hypertension displayed 339 men i.e. 10.2% of the study group. So, borderline hypertension (systolic, diastolic and systolic-diastolic) was found in 933 men which makes 28.1% of the population under the study.

Adult↗

PubMed1984

[Effect of padan on active sodium transport in the epithelium of isolated frog skin].

The effects of " Padan " (hydrochloride of 1.3-di/ carbomylothio /-2-N-dimethylamino/propane/ upon transport capabilities of plasmatic membrane have been checked. The experiment was performed on isolated skin of Rana temporaria frogs. Assessment of transporting activity of membrane in relation to sodium ion involved a method developed by Ussing with so called "short-circuit" technique. The effects of the pesticide on the external and internal surface of the frog's skin have been examined, final concentrations of the compound being 3.4 X 10(-6) M to 3.4 X 10(-3) M. The results indicate that " Padan ", whether administered to the external or internal surface of the membrane, decreases the value of membrane potential and short-circuit current, which is indicative of membrane transport inhibition. The effect varies with pesticide concentration in the medium, though it is statistically significant only in concentration 3.4 X 10(-3) M. On the other hand, membrane resistance usually gets increased as the compound concentration in the medium increases. The results indicate that cellular membrane should be considered while explaining the mechanism of toxic effects of " Padan " upon organism.

Action Potentials↗

PubMed1983

[Effect of bromfenvinphos (IPO-62) on changes in the apical dendritic spines of the cortical pyramidal neurons of the rat].

The rats (control group--6 animals, experimental group I--13, experimental group II--8) of inbred Wistar/W Bog strain, were orally administered 84,6% technical concentrate IPO-62 (bromphenvinphose) dissolved in olive oil and next the spines on apical cortex dendrites were evaluated. Statistically significant loss of dendritic spines was found both in group I (IPO-62 daily dose from 3 to 12 mg per 1 kg of body weight during 58 days) and in group II (IPO-62 daily dose--12 mg per 1 kg/body weight for 5 days and 18 mg/kg body weight for 4 days).

Animals↗

PubMed1982