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Biomedical subjects

M Korbel

Publications and source records attributed to M Korbel.

8 recordsLinked to original sources
PubMed2000

[Laparoscopic findings in women with chronic pelvic pain].

Chronic pelvic pain afflicts 5-10% of women. The diagnosis of its cause is predominantly assessed by means of laparoscopy which in 60-70% reveals various organic causes of pain. The retrospective study analyses the results of 43 laparoscopic examinations indicated due to chronic pelvic pain. The average age of patients was 29.97 years. Organic findings on internal genitals were found in 36 cases (83.7%). Endometriosis was diagnosed in 11 cases (25.6%). According to the criteria of American Fertility Society, 4 patients (36.4%) suffered from stage I, 6 patients (54.5%) suffered from stage II, and only one case (9.1%) was caused by stage III. Chronic inflammatory process was diagnosed in 12 cases (18.6%), adhesions without any other pathologic findings in 8 cases (18.6%), and ovarial cysts in 3 cases (7.0%). Varicose pelvic veins and uterine myoma occurred in one case (2.3%), respectively. In 7 cases, no pathological change was revealed. Laparoscopy in coincidence with chronic pelvic pain is a significant examination which helps to reveal the organic origin of disturbance. An early decision of applying this invasive examination contributes to fast assessment of the diagnose and commencement of treatment. (Tab. 2, Fig. 1, Ref. 32.)

Adult↗
PubMed1999

[Papillomavirus infection of the uterine cervix in women using contraception].

OBJECTIVE: The authors analyze the prevalence of the anogenital form of HPV infection as one of the most frequent STD, in the female population using different types of contraception. METHODS: Using the method of DNA hybridization, the authors examined for HPV infection of the uterine cervix 245 users of contraception, incl. 127 women using hormonal contraception and 118 women with IUD. 112 women of this group were examined before they started to use contraception and one year after started to use it. The control group was formed by 143 using no contraception. RESULTS: The authors found a significantly higher incidence of HPV infection of the uterine cervix in the group of women using contraception (24.1%) than in the control group (15.4%). On analysis of the group of women using contraception, as compared with the control group, they found a significantly higher incidence of HPV in women with hormonal contraception (26.0%) while the higher prevalence of HPV (by 6.6%) in women with IUD as compared with the control group was not significant. However the differences in the incidence of HPV (4%) between the two groups of women taking hormonal preparations (26.0%) or having a IUD (22%) were not significant. On examination of women before the onset of contraception and after one year of its use the authors found that candidates of contraception had as compared with the control group an insignificantly (by 3.3%) higher prevalence of HPV already before the beginning of contraception. After one year of contraception it increased by another 3.6%. CONCLUSION: With regard to the higher incidence of HPV in women using contraception and with regard to the oncogenic effect of HPV the authors emphasize the importance of regular detailed gynaecological examinations of these women focused on early diagnosis of precancerous conditions of the uterine cervix.

Adolescent↗
PubMed1999

Developmental defects and chromosomal aberrations in spontaneous abortions and stillbirths.

The authors analysed 1488 cases of spontaneous abortions and stillbirths in Bratislava. They focused on the course of human embryogenesis and the chromosomal constitution. A high mean frequency rate of both developmental defects (14.4%) and chromosomal aberrations (33.6%) was revealed and both were found to be in close relation with the length of gestation. The most severe developmental defects occurred mostly in early stages of human embryogenesis, i.e. in the 1st trimester of gestation.

Abortion, Spontaneous↗
PubMed1999

Mola invasiva--special form of GTD.

Invasive hydatidiform mole is a relative rare form of gestational trophoblastic disease (GTD). Most of hydatidiform moles remit after evacuation but some of them have the tendency to invade the myometrium. In some rare cases the trophoblastic tissue can be found in other tissues like lungs, vulva, vagina or broad ligament. The aim of the study was to demonstrate some of clinical, immunohistochemical and DNA analysis findings of a patient with a previous diagnosis of a complete hydatidiform mole.

Base Sequence↗
PubMed1998

[Personal experience with diagnosis of complete hydatidiform mole based on DNA].

In our study we analyzed 13 cases of histologically defined complete hydatidiform mole (CHM), by using cytogenetic and molecular genetic methods. There were seven homozygous and six heterozygous CHM. In one case of heterozygous CHM we found a biparental contribution to genomic DNA. This is evidence of a more heterogeneous etiopathogenesis of hydatidiform mole.

DNA, Neoplasm↗
PubMed1998

[Sex life of pregnant women with cardiopathies].

In a retrospective investigation comprising a group of 116 women with cardiopathies who delivered in 1989-1993. The author evaluated their sex life during the early puerperium, using the author's questionnaire "Sexual behavior and cardiac diseases" supplemented by a controlled interview. 41 women (35.3%) refused the interview on sexual behavior and did not complete the questionnaire. The analyzed group comprised 71 women with cardiac diseases. The maternal mortality rate in the investigated group was 0.86%, the perinatal mortality rate 0.0%, prematurity 3.4% and hypotrophy 5.2%. It was revealed that during the pregestation period 80% of the women with cardiac diseases has regular sex at least once a week and had an orgasm and satisfaction without any fears. With advancing pregnancy the libido declines, as well as the frequency of sexual intercourse, orgasm and sexual satisfaction and fear of sexual intercourse increases. Except during pregnancy and at its onset the spectrum of coital positions is varied. At the end of pregnancy lateral positions predominate. Sexual activity before pregnancy is usually initiated by both partners. At the end of pregnancy in first pregnancies it is the woman, in pluriparas it is usually the man. Interest in the sexual behavior of women with cardiac diseases on the part of cardiologists and obstetricians was minimal. In the author's opinion there is no reason to restrict sex life during pregnancy in women with cardiac diseases functional stage I and II (NYHA, 1964) unless there are obstetric or cardiological contraindications.

Adult↗