Biomedical subjects
Publications and source records attributed to M Korenkov.
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OBJECTIVE: To review the tensile strength of the different histological types of fibres in the linea alba and correlate the anatomical features of the anterior abdominal wall with the tensile strength of the linea alba to see whether the tensile strength of the linea alba might contribute to the development of midline incisional hernias. DESIGN: Laboratory study. SETTING: University hospital, Germany. SUBJECTS: 46 cadavers in part one, and 9 freshly frozen and 38 formalin-fixed cadavers in part two. INTERVENTIONS: In the first part of the study the histological examination was by binocular dissection microscopy, magnification x10, but this was not sufficiently reproducible so in the second part we used an Olympus BX50 microscope, magnification x20, and Optimas 5.22 picture processing software. Tensile strength was measured using a Loosenhausen ZHP 1-6 tensiometer. MAIN OUTCOME MEASURES: Correlation between anatomical features and tensile strength. RESULTS: The method used in part one of the study failed to differentiate between the three types of fibres in the linea alba (weak, intermediate, and compact). In the second part of the study we found that the fibres were irregular, with no systematic crossing of the fibres of the aponeurosis. There was a significant correlation between the thickness and density of fibres in the linea alba and its tensile strength (r = 0.9). The thickness of fibres ranged from 21.9-38.2 microm and the density from 48% to 90%. The tensile strength ranged from 3-25 kp. CONCLUSION: A combination of low density and thin fibres in the linea alba could be a predisposing factor for development of midline incisional hernias
We present a patient with a lethal blood concentration of cyanide. Additionally, he was found to have an alcohol blood level of 270 mg. dl-1, but made a complete recovery following administration of the antidotes dimethylaminophenol and thiosulphate. It is postulated that the patient may have been able to detoxify himself as a result of metabolism of cyanide to the non-toxic form, thiocyanate.
A case of combined abdominal wall paresis and incisional hernia after laparoscopic cholecystectomy is reported. The paresis possibly occurred by a lesion of the N. intercostalis when extending the incision for stone extraction. Possibly the paresis was a predisposing factor for the development of an incisional hernia. The causes of abdominal wall paresis are explored with a review of the literature. In spite of minimal trauma to the anterior abdominal wall in laparoscopic procedures, the risk of iatrogenic lesions remains.
We investigated the accuracy of combined physical and color duplex sonographic examination in the preoperative distinction of direct inguinal hernias. After a learning period (with 15 male patients) 50 consecutive male patients who underwent surgery in our department for small inguinal hernias between July 1995 and April 1996 were examined. On color duplex examination the relationship between the hernial sac and the inferior epigastric artery was determined. Intraoperative results were then compared with the data obtained preoperatively. The sensitivity of our physical examination for direct inguinal hernia was 75% with a specificity and a positive predictive value of 100% and a negative predictive value of 80%. The identification of the IEA as well as the hernial sac was successful on every color duplex sonographic study. The sensitivity of color duplex sonography for direct inguinal hernias amounted to 90%, the specificity was 86%, the positive predictive value was 78%, and the negative predictive value was 89%. Both combined hernias found intraoperatively had not been detected either by physical examination or by color duplex examination. Correspondence of results obtained by physical examination and color duplex examination leads to high accuracy in the diagnosis of direct inguinal hernias.
OBJECTIVE: To evaluate the current practice of incisional hernia repair in Germany and analysis of the results of the Mayo duplication technique done in our hospital over a 10-year period. DESIGN: Nationwide survey, retrospective analysis. SETTING: University department, Germany. SUBJECTS: Survey of most surgical departments and of 114 patients with 135 incisional hernias in our unit. INTERVENTION: Mayo duplication repair incisional hernias. MAIN OUTCOME MEASURES: Common practice, recurrence rates, quality of life. RESULTS: The Mayo overlap is the preferred technique in most surgical departments. The estimated failure rates (12% or less) in general practice are grossly underestimated. In our hospital the recurrence rate after Mayo duplication repair was 61/114 (54%) during a follow up time of 5.7 years with a follow-up-rate of 84%. Univariate and multivariate analyses failed to identify any predisposing factors. All patients with incisional hernias had limitations their physical function. CONCLUSIONS: The widely used Mayo procedure leads to unacceptable results for repair of incisional hernias and other techniques should be evaluated and used more often. Repair of an incisional hernia does not improve overall quality of life.
All 1994 publications of four leading journals in surgery, orthopedics and internal medicine in Germany (Der Chirurg, Der Unfallchirurg, Langenbecks Archiv für Chirurgie, Medizinische Klinik) were reviewed by means of a structured analysis. The type of article, authorship, number of references, geographical location, quality, and main conclusion (positive; neutral; negative) of each article were documented. The journals focused on clinical studies (32.2-59.6%), case reports (11.0-26.1%) and reviews (6.4-40.9%). Articles about surgical techniques were mainly found in Der Chirurg (16.9%), experimental studies in Der Unfallchirurg (14.7%) and Langenbecks Archiv für Chirurgie (25.7%). Most articles were written by university clinic personnel (62.6-81.4%). In 11.0-22.6% of all articles, the head of a clinic was the first author and the co-author in 36.5-58.7%. Women were found to be first author in 4% in surgery, and in 10.4% in internal medicine. Of a total of 495 publications, 53.9% were written in Northrhine-Westphalia, Bavaria or Baden-Württemberg and only 1.6% in the five new federal states. Of all articles 16.4% were by foreign authors, with 10.5% originating from German-speaking countries. The portion of controlled randomized trials ranged between 4.9% (Der Unfallchirurg) and 11.3% (Der Chirurg) of all published studies. Studies and case reports with negative results were found to be more evident in Der Chirurg and Langenbecks Archiv für Chirurgie (ca. 20%) as compared to Der Unfallchirurg and Medizinische Klinik (ca. 6%). All journals provided good general information about the actual developments in a variety of topics to the reader. However, some improvement concerning international contributions, participation of the new federal states, and the quality of studies is recommended.
About 10% of patients undergoing conventional laparotomy will develop incisional hernias. Traditionally these hernias are in this country most often repaired by a Mayo-duplication. In this retrospective analysis we investigated a consecutive series of 114 patients (mean age: 53 (11-87) years, gender ratio m:f 1.2:1.97% electively operated) with 135 hernias, operated between 1/1985 and 12/1992 by a standard Mayo-procedure. Recurrence-rates and quality of life were evaluated by clinical examination. The mean follow-up time was 5.7 (2.5-10.2) years with a follow-up rate of 84.4%. The overall recurrence rate was 53.5%. Further uni- and multi-variate analysis was unable to find any clinically relevant risk factors for hernia development. Health related quality of life was evaluated with a validated index at the time of their follow-up visit. There were no differences in patients without a hernia recurrence (n = 52) when compared to those with an actually present recurrence (n = 36). However, physical function of all patients was significantly impaired when compared to healthy individuals. According to our results and those reported by others the Mayo-duplication when applied to all patients leads to non-acceptable results and implantation of auto- or alloplastic material should be considered more frequently.
The recurrence rates following the "simple" incisional hernia repair procedures (Mayo-procedure or direct adaptation) are unacceptably high, in literature up to 50%. In order to reduce the recurrence rates alternative procedures are necessary, e.g. the additional support of the anterior abdominal wall by implantation of a non resorbable mesh or autodermal plasty. Our national inquiry of 669 hospitals showed that the technique of autodermal hernioplasty is almost unknown among the German surgeons. In this article a comparison of the history, morphology, healing process and possibilities of cutis implantation as well as technical aspects of different types of autodermal hernioplasty (cutis lacing plasty, onlay and sublay corium mesh plasty) are described. By literature analysis the results of autodermal hernioplasty are compared with the results of mesh implantation. The autodermal hernioplasty is discussed as an alternative operative procedure to the implantation of artificial meshs.
BACKGROUND: The technique of laparoscopic adjustable gastric banding (LAGB), although relatively well standardized, has some "weak points". METHODS: We analysed the experience of 2 German university clinics in order to suggest technical alternatives that can be helpful in difficult situations. RESULTS: Between April 1997 and May 2002 115 patients in Cologne (87 females, 28 males) with median BMI 49.5 kg/m(2) and mean age 39 years (19-54), and 112 patients in Mainz (91 females, 21 males) with median BMI 48 kg/m(2) and mean age 35 years (18-57) underwent LAGB, using the Lap-Band. LAGB was performed through 5 ports (3 10-mm, 1 18-mm, and 1 5-mm in Cologne and 4 10-mm and 1 18-mm port in Mainz). The pars flaccida technique by means of a fan-shaped Endo-Retractor was used in both clinics. Mean duration of follow-up was 3.2 years (SD 1.0) in the Cologne group with complete investigation in all except 4 patients. In the Mainz group, mean duration of follow-up was 2.7 years (SD 1.0) with complete investigation in all except 9 patients. CONCLUSIONS: Some technical aspects such as induction of pneumoperitoneum, band position, band fixation, band malposition and port-related complications are discussed.