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Biomedical subjects

M Kornberg

Publications and source records attributed to M Kornberg.

At least 19 recordsLinked to original sources
PubMed1995

Nerve root compression by a ganglion cyst of the lumbar anulus fibrosus. A case report.

STUDY DESIGN: A case report of a ganglion cyst rising from the anulus pulposus, causing lumbar nerve root compression. OBJECTIVES: A rare pathologic condition causing sciatica is described. The pathologic anatomy and the magnetic resonance image of the lesion is discussed. SUMMARY OF BACKGROUND DATA: A 35-year-old man was subjected to an abrupt twisting motion of the torso during a motor vehicle accident. The patient had a L5-S1 discectomy 1 year before the accident. His low back discomfort and right lower extremity pain were clearly exacerbated by the recent trauma. METHODS: Magnetic resonance imaging revealed enhancing lobulated epidural mass displacing the S1 nerve. RESULTS: Intraoperative findings were a lobulated cystic mass rising from the degenerated anulus fibrosus, determined on histologic examination to be a ganglion cyst. The patient noted significant relief of the right sciatica after surgery. CONCLUSION: The appearance and the signal intensity of the epidural mass appear to be important parameters in diagnosing the presence of a ganglion cyst of the anulus fibrous. Excision of the ganglion cyst is indicated in a patient who fails to respond to conservative treatment and where the symptoms correlate with the abnormality seen with magnetic resonance imaging.

Adult↗
PubMed1992

A recurrent marker chromosome involving chromosome 1 in two mammary tumors of the dog.

An apparently identical marker chromosome resulting from a chromosome 1. translocation was found in the mammary carcinomas of two bitches. Although these karyotypic aberrations were the sole clonal aberrations detected, it was not possible to unambiguously identify the material translocated to the chromosome 1 in either animal. Our observations, however, represent the first report of a recurring marker chromosome in mammary tumors of the dog and suggest that these tumors may become an interesting model for human breast cancer.

Animals↗
PubMed1989

[Electromyography and spinal evoked potentials in cauda equina syndrome of dogs].

In order to investigate usefulness of electrodiagnostic methods in Cauda Equina-Compression, 26 dogs with this disease were subjected to electromyography and spinal evoked potentials. 16 normal dogs served as controls. It was found that--after stimulation of the Nn.tibialis, peronaeus, pudendus and coccygeales and recording at the lumbosacral junction--latencies and nerve-conduction velocities were largely normal. However the amplitudes were decreased and--depending on the severity of the compression--the morphology of the potentials was altered although considerable standard deviations were obtained. Electromyographically, increased spontaneous activity with fibrillations and positive sharp waves were found in the myotomes of the lumbosacral nerves. Their number increased according to the severity of the cauda equina compression and they had a centrifugal distribution pattern. Based on these results it appears indicated to perform an electromyographic exam before applying myelography. The technique of spinal evoked potentials will need more refinement and standardisation before being useful in a clinical situation.

Animals↗
PubMed1987

Computed tomography in the postoperative lumbar spine.

A retrospective review of computed tomograms (CT) was performed in eight patients who underwent surgery for presumed reherniation of a lumbar disc. The CT scan in the three patients with surgically proven extradural scarring and no disc herniation, demonstrated distinct characteristics of perineural fibrosis which differed markedly from the uniform changes seen on the scans of the five patients with proven herniation.

Adult↗
PubMed1986

Atypical unstable burst fracture of the atlas. Treated by primary atlantoaxial fusion.

Burst fracture of the atlas with concomitant disruption of the transverse ligament is presented by the author because it demonstrated an atypical fracture pattern on computed tomography that has bearing on the treatment modalities. The integrity of the posterior arch was preserved, except for a fracture in the proximity of one of the lateral masses. The patient underwent a posterior C1-C2 fusion before there was evidence of healing of the posterior arch fracture. The fracture healed, and a good C1-C2 fusion was noted.

Adult↗
PubMed1985

Hand and wrist joint problems in patients with Ehlers-Danlos syndrome.

Ehlers-Danlos syndrome is a heritable disorder of connective tissue that is clinically characterized by joint hypermobility and skin hyperextensibility and fragility. Four of our patients who fit the criteria for Ehlers-Danlos syndrome are presented. Abnormalities in the hand and wrist joint that are directly related to joint hypermobility are discussed.

Adult↗
PubMed1985

Quantitative assessment of the fifth lumbar spinal canal by computed tomography in symptomatic L4-L5 disc disease.

Interpedicular distance, interfacet distance, midsagittal diameter, and cross-sectional area at the upper aspect of the fifth lumbar spinal canal were measured from the computed tomographic (CT) scans of the spine performed in a period of 1 year. The patients were divided into four groups. Group I (25 patients) was the normal control group. Group II comprised 29 symptomatic patients who were thought to have an L4-L5 herniated nucleus pulposus (HNP) by CT and did not undergo surgery. Group IIIA was made up of 24 patients who underwent an L4-L5 discectomy and had favorable results, and Group IIIB (3 patients) included those who failed to improve following surgery. The symptomatic patient with an L4-L5 HNP by CT who did not undergo operative treatment had a mean canal size as measured by midsagittal diameter and cross-sectional area that was smaller (P less than 0.05) than in a normal control group. In the patients who required an L4-L5 discectomy, these same measurements were smaller (P less than 0.001) when compared with the nonoperative group. In the three failure patients, all four measurements were significantly smaller than in patients in Group IIIA with the interfacet distance and the cross-sectional area differences being the greatest (P less than 0.001). The patients who are likely to undergo operative treatment have a midsagittal diameter that is less than 1.6 cm and a cross-sectional area that is less than 2.5 cm.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗