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Biomedical subjects

M Korsić

Publications and source records attributed to M Korsić.

46 records · Page 3Linked to original sources
PubMedDate not supplied

[The role of the TRS-Glucotest apparatus in self-monitoring by patients with diabetes mellitus].

Successful treatment of diabetes mellitus requires a reliable control of glycaemia where self-monitoring with reflectometer plays a significant role. TRS-glucotest reflectometer (TRS, Zagreb), the result of our experts' efforts, makes it possible for diabetic patients to perform self-monitoring. According to our research TRS-glucotest reflectometer shows lower blood glucose levels for more than 20%, especially in 3.8-11.5 mmol/L range of glucose concentration, that is in the range most often expected in patients with diabetes got under control. A considerable dispersion of the results got by measuring glucose levels with reflectometer doesn't offer the possibility to correct the obtained values. Our results suggest that TRS-glucotest reflectometer should be improved so that reliable control of glycaemia can be made what is especially important in patients with intensive conventional insulin treatment.

Aged↗
PubMedDate not supplied

[Obesity].

Explore the source record for details and available documents.

Humans↗
PubMedDate not supplied

[The effect of menopause and age on bone mineral density in women living in an urban environment in northern Croatia].

The results of measurement of bone mass in three areas (lumbar spine, femoral neck and radius) where osteoporotic fractures most commonly occur are presented. The sample of 103 women was divided into three groups: premenopausal, early menopausal (up to 5 years of menopause) and late menopausal (more than 5 years of menopause). Both menopausal groups were additionally divided in two subgroups regarding the previous fractures. A statistically significant difference (p < 0.01) was found between bone mineral density (lumbar spine, femoral neck) and bone mineral content (radius) among all the groups. No difference was established for bone mass between postmenopausal women with and without fractures (> 0.05) by using the Kruskal-Wallis analysis of variance. A significant negative correlation (p < 0.01) was found between bone mass in all three tested regions on one side vs age of women as well as the period of menopause on the other. These results indicate that bone mass is significantly decreased in postmenopausal women. Therefore, the authors recommend densitometry to be employed in all postmenopausal women.

Adult↗
PubMedDate not supplied

[Arterial hypertension in the obese--aspects of etiopathogenesis].

Many epidemiological and clinical studies show a strong association between arterial hypertension and obesity. The underlying pathophysiological mechanism is unknown. It is thought that the etiopathogenesis of obesity hypertension is exceptional and in that view hormonal, neural, volume and hemodynamic properties of obesity, as well as salt and/or caloric consumption, are outlined. In this article all these factors are discussed. According to the current hypothesis, hyperinsulinemia which is probably a physiologic adaptation to obesity, plays a key role in the pathogenesis of arterial hypertension. Insulin increases the reabsorption of sodium by means of an immediate effect on the kidney tubules. An increase of sodium in the body leads to hypervolemia and to the elevated blood pressure. Chronic hyperinsulinemia perhaps increases the blood pressure indirectly also by means of the central nervous system, namely, by stimulating the activity of the sympathetics.

Humans↗
PubMedDate not supplied

[Metabolic bone disease in a female patient with gluten enteropathy].

A 41-year old female patient with metabolic bone disease is presented. The disease was caused by malabsorption which developed as a result of gluten induced enteropathy. The diagnosis was confirmed by histological finding of the small intestine mucosa and bones. Following gluten-free diet, calcitriol and calcium tablets, the patient started to move independently and the bone mineralisation improved.

Adult↗
PubMedDate not supplied

[Metabolic diseases and the high-fiber diet].

There is no doubt that fiber, in particular viscous dietary fiber, has a positive effect on human health both in the prevention and treatment of chronic diseases. Over 30 years of intensive clinical research with guar, psyllium, oat and other fiber-rich foods has repeatedly demonstrated the health benefits of dietary fiber in lowering insulin requirements and improving blood glucose control in diabetics, as well as reducing serum lipid levels in hyperlipidemics. Accumulating epidemiological evidence is also supporting the link between high-fiber diets and the reduction of risk for heart disease and cancer. As a result, increased dietary fiber is recommended by health authorities worldwide. However, the mechanism of fibers' action is not fully understood and the effect is not always consistent with the expected results. One of the reasons could be the large intra- and inter-fiber variability due to its complex structural and physicochemical characteristics. As a consequence, some of the health agencies focus their recommendations more on the type of dietary fat rather than a high carbohydrate/high-fiber.

Coronary Disease↗
PubMedDate not supplied

[Parameters of thyroid gland function in acute myocardial infarct].

In 31 patients with acute myocardial infarction triiodothyronine (T3), free triiodothyronine (FT3), thyroxine (T4), free thyroxine (FT4), thyrotropin (TSH) and TBG were measured and T3-test was performed on the 1st and the 10th day of hospitalization. The 1st day values for T3, FT3 and TBG were significantly lower, and T4 and TSH were significantly higher than in the control group. The same differences were noted on the 10th day for T3, FT3 i T4. TBG was significantly higher than the 1st day. TSH was lower and it was not significantly different from control values. These results are compatible with clinical observations described in severe nonthyroidal illnesses.

Aged↗
PubMedDate not supplied

[Turner's syndrome--case report of a female patient with chromosome mosaicism].

A 45-year old woman with the typical Turner's phenotype (short stature, short and broad neck, shield chest and low hairline) and signs of ovarian failure started at the age of 37 with menopause at the age of 44, is presented. The cytogenetic analysis showed the presence of three different cell lines with 45,X, 46,XX and 47,XXX karyotypes. It is a rare type of mosaicism, combining Turner's and triple-X syndrome. Interestingly, the became pregnant and gave birth to a healthy child. Second pregnancy resulted in a miscarriage in the first trimester.

Female↗