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Biomedical subjects

M Kost'ál

Publications and source records attributed to M Kost'ál.

18 recordsLinked to original sources

[Pregnancy in a woman with short intestine syndrome on long-term parenteral nutrition--case report].

OBJECTIVE: To report our experience with long-term parenteral nutrition in pregnancy. SUBJECT: Case report. SETTING: Department of Obstetrics and Gynecology, Department of Geriatrics and Metabolism, Department of Paediatrics, Medical Faculty of Charles University and Faculty Hospital, Hradec Králové. SUBJECT AND METHOD: We describe successful pregnancy in a woman on long-term parenteral nutrition. CONCLUSION: Total parenteral nutrition is effective and safe method, which can solve maternal malnutrition and provide optimal conditions for fetal growth and development.

Adult↗

Cardiac troponin T in neonates after acute and long-term tocolysis.

The present study was designed to determine the levels of cardiac troponin T (cTnT) in cord blood of neonates exposed in utero to tocolytic therapy by beta-sympathomimetics. cTnT in 40 neonates after acute tocolysis (0.24 +/- 0.05 microg/l) was significantly higher (p < 0.05) in comparison with the control group (0.05 +/- 0.01 microg/l). The maximal values were reached in about the 3rd day of therapy (0.39 +/- 0.11 microg/l). cTnT in 30 neonates after long-term tocolysis was 0.12 +/- 0.03 microg/l. No correlation was found between cTnT and CK and its isoenzyme CK-MB or ECG. CK, unlike cTnT, significantly correlated with gestational age (r = 0.57, p < 0.05) and birth weight (r = 0.55, p < 0.05). It is possible to conclude that acute tocolytic therapy by beta-sympathomimetics increases the cTnT levels in cord blood and cardiac troponin T is more useful for the laboratory diagnosis of neonatal myocardial injury than CK-MB.

Adrenergic beta-Agonists↗

[Troponin T levels in cord blood after tocolysis with Bricanyl].

The present study was designed to evaluate the side-effects of preventive tocolysis by Bricanyl on the foetal myocardium using the new serological marker of myocardial damage-troponin T (TnT). The cardiac troponin T concentration was measured by means of commercial kits (Enzymun-Test System, Boehringer Mannheim, Germany) in the cord blood of 15 neonates. TnT serum concentration of neonates exposed in utero to Bricanyl was not significantly higher (mean 0.12 +/- 0.20 microgram/l) in comparison with the normal cardiac troponin T level but 4 of 15 neonates had an elevated TnT concentration (above 0.1 microgram/l). No correlation was found between TnT and CK or CK-MB.

Female↗