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Biomedical subjects

M Kozłowski

Publications and source records attributed to M Kozłowski.

9 recordsLinked to original sources
PubMed1992

Evaluation of squamous cell carcinoma antigen (SCC-Ag) in the diagnosis and follow-up of patients with non-small cell lung carcinoma.

The usefulness of squamous cell carcinoma (SCC) antigen as a tumor marker was investigated in 72 patients with histologically verified non-small cell lung carcinoma (NSCLC). Increased level of SCC-Ag was observed in 41%, mostly in patients with squamous cell carcinoma (69%). Positive serum SCC-Ag was correlated with lymph node metastases and with the stage of disease. The positive rate of SCC-Ag observed in patients without and with nodal metastases was 52.9% and 84.2%, respectively. Positive SCC-Ag level was observed in 50% of Stage I, 71.4% of Stage II and 78.9% of Stage III patients with squamous cell carcinoma of the lung. The study proved that preoperative SCC-Ag determination in patients with squamous cell carcinoma of the lung and the course of levels of this marker during postoperative follow-up was of importance. A high preoperative and postoperative SCC-Ag value suggested a worse prognosis.

Antigens, Neoplasm↗
PubMed1992

Value of CEA and SCC-Ag in bronchoalveolar lavage (BAL) and serum of patients with lung carcinoma.

To evaluate the diagnostic usefulness of simultaneous determinations of carcinoembryonic antigen (CEA) and squamous cell carcinoma antigen (SCC-Ag), we studied 25 patients with lung carcinoma and 12 with nonmalignant lung diseases. The measurements were made in serum and bronchoalveolar lavage (BAL). The results showed that positive rates with lavage CEA and SCC-Ag in lung carcinoma patients were higher in comparison with those markers in serum. The combination of lavage CEA and SCC-Ag taken together with the results of bronchoscopy (histology and cytology) showed the highest discriminating power between malignant and nonmalignant lung diseases. The sensitivity of bronchoscopy increased from 48 to 84% with at least 1 positive marker. It appears that the simultaneous determination of CEA and SCC-Ag levels in serum and BAL in lung carcinoma patients may be of considerable importance in diagnosis.

Adenocarcinoma↗
PubMed1990

[Interferon--clinical application].

In another of a series of papers on interferon the authors review the treatment with synthetic interferon of viral and neoplastic diseases. The method of interferon obtaining on an industrial scale is described.

Humans↗
PubMed1979

[Improvement in the quality of rape seed by combining silage with fodder sugar beets. 1. Quality evaluation of the silages].

Industrial-scale studies showed that the addition of rape-seed flakes to half sugar mangels improves the feeding value and the quality of the silages. Furthermore, it was found that the development of yeasts was inhibited and that the propagation of acidifiers was retarded as the proportion of rape-seed increased. The microbiological analysis indicates that the amount of rape-seed added to the half sugar mangels should not exceed 10%.

Animal Feed↗
PubMed1979

[Improvement in the quality of rape seed by combining silage with fodder sugar beets. 2. Changes in glucosinolate derivatives and fat contents].

Industrial and laboratory-scale studies showed that the combined silage fermentation of rape-seed flakes with half sugar mangels leds to a very beneficial reduction in the content of glucosinolate derivatives, especially during the first week of fermentation and storage processes on the qualitative and quantitative fatty-acid parameters were but significant.

Animal Feed↗