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Biomedical subjects

M Kozakiewicz

Publications and source records attributed to M Kozakiewicz.

11 recordsLinked to original sources
PubMed2001

Cherubism--clinical picture and treatment.

UNLABELLED: Cherubism is a rare, painless, disfigurating disease primarily affecting bones of the jaws. OBJECTIVE: To report on five patients with cherubism. The symptoms of the disease, methods of management and possible mode of inheritance are discussed and literature is reviewed. PATIENTS: The study involves five cherubs, members of one family. The diagnoses were based on history, physical examination, laboratory tests, X-ray parameters, and clinical follow-up. One member of the family had surgical intervention. The remaining cases were left for observation. RESULTS: Good aesthetic and long lasting effect was reached in the operated patient. CONCLUSIONS: Treatment is unnecessary unless functional or emotional disturbances develop. An autosomal recessive pattern of inheritance is suggested for these cases, although autosomal dominant transmission has been previously established.

Adolescent↗
PubMed2001

The effects of unilateral and bilateral neurectomy of inferior alveolar nerves on the frequency of PCNA-positive keratinocytes in basal layer of gingival epithelium in Lewis rats.

The aim of our study was to establish the role of sensory denervation on gingival epithelium proliferation. We investigated the effect of unilateral (right side) and bilateral neurectomy of inferior alveolar nerve on PCNA-positive (PCNA+) cell frequences in the basal layer of gingival epithelium in male Lewis rats. The samples were taken in each group both from left and right side of gingiva, and the PCNA+ cells were counted separately in the epithelium from both sides in all groups. The results of our study indicate that the proliferation of gingival epithelium, expressed as percentage of PCNA+ nuclei of basal layer keratinocytes of gingival squamous epithelium, is better correlated with the trauma than with denervation.

Animals↗
PubMed2001

Mast cell distribution and density in Lewis rat gingiva after bilateral neurectomy of inferior alveolar nerves.

The effect of uni- and bilateral neurectomy of inferior alveolar nerve on mast cell (MC) density and topography were studied in Lewis rat gingival mucosa. The results were compared with unilateral sham operation effects. The samples were taken in each group both form left and right side of gingiva, MC were revealed by pinacyanol erythrosinate and counted in connective tissue adjacent to the basal membrane of gingival epithelium. MC were insensitive to sham operation and the differences were noted only in MC density after unilateral neurectomy between both sides of gingiva, and in distribution between the control and left side after bilateral neurectomy. The results suggests that neurectomy and sham operation trauma after 3 weeks have limited effect on mast cell density and distribution.

Animals↗
PubMed1998

Small mammal populations and community under conditions of extremely high thallium contamination in the environment.

Studies were carried out in the vicinity of a zinc smelter in southern Poland, 50 km northwest of Krakow, where the previous measurements with another bioindication method revealed huge thallium levels in the environment. The mammals (106 individuals in total) were captured in four wooded areas situated 1.5 to 2.5 km in various directions from the plant and in two reference sites, located far from industrial emission sources. Very high Tl levels were found in livers and kidneys of all mammals examined from the two areas nearest the smelter. Bank voles were the most loaded (maximum Tl in kidneys, 34.27 microgram/g dry mass; in livers, 14.53 microgram/g; values from unpolluted areas were below the detection limit, 0.07 microgram/g). A distinct decrease in the amount of hair-a characteristic of thallium poisoning-was observed in several individuals. The extreme case was a wood mouse with the rear half of its body almost entirely hairless (!). Densities of single populations and the whole community were very low, up to 4.8 individuals/ha, including insectivores. Numerical proportions between species were changed in comparison to unpolluted areas. The age structure was deformed, with a disproportionate small participation by young generations. Among the males studied, only sexually inactive individuals were found. The condition of populations and the community of small mammals living here was much worse compared with data from the surroundings of other zinc smelters.

Alopecia↗