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Biomedical subjects

M Kuhnke

Publications and source records attributed to M Kuhnke.

5 recordsLinked to original sources
PubMed2001

Micro flow modules with combined fluid flow channel and optical detection waveguide--hyper Rayleigh scattering as a case study.

Micro flow modules with optical detection have been fabricated in a way which enables optical waveguiding inside and a defined interaction length along the fluid channel. Because of the usually lower refractive index of the solution compared with that of the substrate, so-called "leaky" optical wave-guiding must be employed. The combination of the fluid flow channel function with that of the optical waveguide has advantages for all miniaturized optical detection cells. It has been shown for hyper Rayleigh scattering (HRS) that improvement of the analytical principle is inherent in the miniaturization. The detection limit can be enhanced by at least a factor of 20. The applied HRS measurement procedure also enables simultaneous detection of two photon absorption (TPA) fluorescence. The severe boundary conditions of capillary electrophoresis were used as micro flow module design constraints to enable the transfer of the approach to other types of analysis.

Journal Article↗
PubMed2000

Laparoscopic repair of cholecystoduodenal fistula: report of two cases.

BACKGROUND: Laparoscopic surgery has become the standard of care for benign gallbladder disease. PATIENTS AND METHODS: We treated two middle-aged women having acute exacerbations of chronic gallbladder disease with laparoscopic cholecystectomy. A cholecystoduodenal fistula was diagnosed intraoperatively in each case. These fistulae were repaired laparoscopically using an endoscopic stapling device without complication. RESULTS: Each patient did well postoperatively and was discharged to home on the second postoperative day in good condition. CONCLUSIONS: Biliary-enteric fistula is a known complication of chronic gallbladder disease that is traditionally considered a contraindication to laparoscopic cholecystectomy. However, we believe laparoscopic repair to be a safe and effective approach in the hands of surgeons with significant laparoscopic experience.

Adult↗
PubMed1987

Herniation of the gastric wall through a Nissen fundoplication.

Two patients presented several years after Nissen fundoplication with dysphagia and/or hemorrhage. In both, the fundoplication was intact in the original relationship to the cardia but herniated gastric wall was found between the fundic wrap and the distal end of the esophagus. The diagnosis and alternatives for preventing this problem are presented.

Aged↗
PubMed1987

Acute transanal ileal evisceration.

This is the 31st report of spontaneous transanal evisceration of small bowel. This case is unique because a rectal prolapse had been repaired previously and at the time of evisceration, there was no evidence of recurrence. Inherent or acquired weakness of the anterior rectal wall combined with a sudden increase in intra-abdominal pressure appears to precipitate this rare phenomenon. Attention to basic surgical tenets applies in the management of this condition.

Adult↗