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Biomedical subjects

M Kulkumthorn

Publications and source records attributed to M Kulkumthorn.

3 recordsLinked to original sources

Cryptosporidiosis among orphanage children in Thailand: a one year prospective study.

The prevalence of cryptosporidiosis and other parasitic infections was studied among the orphanage children in Nonthaburi province, Thailand, during May 1986--April 1987. Cryptosporidium oocysts were detected in fecal specimens of 22 out of 303 diarrheal cases (7.3%) by using a modified cold Kinyoun acid-fast technique. None were found among 513 children without diarrhea. Most of the cryptosporidiosis cases were those under 3 years old. The duration of diarrhea in 20 cases varied from 1 to 25 days (mean = 6.6 days). All cases recovered uneventfully without repeated infection. No sexual preponderance was found. Most of the infections were documented during March to June when both temperature and rainfall were high. It was also noted that these children had high rates of other parasitic infections, 38.1% of the total population. Thus, cryptosporidiosis was not uncommon among children with diarrhea and could be detected almost throughout the year.

Adolescent↗

Albendazole for the treatment of human gnathostomiasis.

The efficacy of albendazole was investigated in 112 patients with symptomatic gnathostomiasis; 49 received 400 mg twice daily, 51 received 400 mg once daily, and 12 patients received placebo, all for 21 d. Subsequent follow-up was for 6 months. Cure (no further swelling) was seen in 93.9% and 94.1% of the treatment groups but in none of the placebo group. Additionally, reductions in eosinophil counts and in immunoglobulin G antibody were observed after treatment. Side effects were minimal. Albendazole may be an effective compound for the treatment of gnathostomiasis.

Adolescent↗