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Biomedical subjects

M Kuratsune

Publications and source records attributed to M Kuratsune.

At least 55 records · Page 3Linked to original sources
PubMed1978

Utilization of records of the National Health Insurance programs for study on cancer morbidity and survival.

Potential value of the records of National Health Insurance programs for study on cancer morbidity was investigated by examination of those preserved in two towns in Japan. By using such records, population at risk and incidence of cancer can be readily and precisely determined. Deaths with load of cancer and survival rate of cancer were also determined without difficulty. In spite of a few limitations involved in the use of records, they are considered to be highly valuable for study on cancer morbidity and survival, mainly due to absence of under-reporting and to the feasibility of obtaining medical and other informations pertaining to cancer patients throughout the specific period.

Adolescent↗
PubMed1976

A cohort study on mortality from cancer and other causes among workers at a metal refinery.

A non-concurrent prospective study was made on deaths from cancer and other causes occurring among 2,675 male workers at a metal refinery from 1949 to 1971. The expected number of deaths computed by applying age- and cause-specific death rates of Japanese males to these workers was compared with the observed number of deaths. Among 839 copper smelters, significantly increased mortalities were noted for lung cancer (SMR = 1,189) and colon cancer, but nor for cancer of the stomach, liver (primary) and biliary passages, pancreas and skin or for leukemia, tuberculosis, cerebrovascular diseases, heart diseases and liver cirrhosis. A dose-response relationship was demonstrated between the mortality from lung cancer and the degree of exposure. A very high excess mortality from lung cancer (SMR = 2,500) was seen among copper smelters who were considered to have been most heavily exposed to arsenic or workers who had engaged in sintering and blast furnace operations for 15 years of more before 1949. The latent period of lung cancer was 37.6 years on average, and not related to level of exposure. Twenty-six of 29 deaths from lung cancer among copper smelters occurred after they had left the refinery. Other production workers and clerical workers showed no significant excess mortality from any kind of cancer.

Colonic Neoplasms↗
PubMed1976

Methylguanidine content in food.

A combination of column chromatography using microcrystalline cellulose and ion-exchange resin, paper chromatography, gas chromatography, and gas chromatogrraphy-mass spectometry was used to determine the content of methylguanidine in various meats of fish and animals, and their processed products. All the samples of fresh fish meat and beef analyzed contained trace amounts (0.2 approximately 0.9 ppm) of methylguanidine. Various types of dried or canned fish also contained trace amounts, while most of the "Bushi-rui," a highly processed dried meat of bonito, mackerel, or sardine contained 21 to 106 ppm of the compound. Two brands of peptone made by digesting meat probably with pepsin and trypsin also contained 12 and 70 ppm of methylguanidine, respectively. Samples of ham, sausage, salami sausage, powdered skim-milk, and a few others did not contain any detectable amount (less than 0.2 ppm).

Food Analysis↗