[Infections caused by Bacteroides fragilis resistant to clindamycin: 2 further cases].
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Biomedical subjects
Publications and source records attributed to M Kwantes.
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The authors report a case of meningitis, presenting all characteristics of the disease described in 1944 by P. Mollaret, occurring in a child aged 2 years and 8 months. They stress the rarity of cases on childhood. The cells found in the cerebrospinal fluid, photographs of which are included, are fragile and may undergo early lysis. They are present in association with lymphocytes and polynuclears, giving the slide examined a highly characteristic mottled appearance. The authors raise the question of the morphological similarity of these large cells, with their polygonal contour and small central nucleus, with an epithelium.
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The authors analyse 42 cases of bacteroides infection regrouping bacteremia and localised infection collected over a period of one year. The route of entry was almost always digestive. The prognosis seems mainly to depend on the background. The bacteriological diagnosis is now easy and germ-sensitivy is stereotyped.
Two cases of fulminating pneumococcal septicemia (FSP) are reported, and 47 confirmed cases were discovered after a review of the published literature. The syndrome is that of a malignant infection with fever, collapse, and disseminated intravascular coagulation, with a rapid mortal outcome in most cases. Etiologically, FSP is usually the consequence of functional or anatomical asplenia, and the relative frequency of this affection after splenectomy following trauma confirms this observation. Lack of a splenic filter and a deficiency in the phagocytic system are the reasons for microbial proliferation in the blood, and the lymphocytic defence mechanisms are inactive because of the absence of any focus of infection.