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Biomedical subjects

M L Abercrombie

Publications and source records attributed to M L Abercrombie.

8 recordsLinked to original sources

The difficulties of changing.

In general, our psychological equipment develops in such a way that we get information of predictive value through the senses; we tend to record constancies and consistencies of events and behave as though these are persistent. We are mostly unaware of the power of the stores of relevant experience (assumptions, expectations, attitudes) that condition our perceptions and therefore cannot question them, nor in many circumstances is there need to do so. In fairly constant conditions they are useful in helping us to see, quickly and effortlessly, what we expect to see. But in rapid changes this is not so; we can no longer rely on our psychological equipment and we become uncertain, confused and, in extreme cases, antagonistic, fearful and impotent. Examples of assumptions that influence medical education and medical treatment are given. Ability to respond effectively to change requires confidence to examine and restructure basic assumptions. The value of interaction in small groups in helping to achieve this is indicated.

Adaptation, Psychological↗

Evaluation of EMIT and RIA high volume test procedures for THC metabolites in urine utilizing GC/MS confirmation.

Results of EMIT, Abuscreen RIA, and GC/MS tests for THC metabolites in a high volume random urinalysis program are compared. Samples were field tested by non-laboratory personnel with an EMIT system using a 100 ng/mL cutoff. Samples were then sent to the Army Forensic Toxicology Drug Testing Laboratory (WRAMC) at Fort Meade, Maryland, where they were tested by RIA (Abuscreen) using a statistical 100 ng/mL cutoff. Confirmations of all RIA positives were accomplished using a GC/MS procedure. EMIT and RIA results agreed for 91% of samples. Data indicated a 4% false positive rate and a 10% false negative rate for EMIT field testing. In a related study, results for samples which tested positive by RIA for THC metabolites using a statistical 100 ng/mL cutoff were compared with results by GC/MS utilizing a 20 ng/mL cutoff for the THCA metabolite. Presence of THCA metabolite was detected in 99.7% of RIA positive samples. No relationship between quantitations determined by the two tests was found.

Dronabinol↗