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Biomedical subjects

M L Diament

Publications and source records attributed to M L Diament.

At least 19 recordsLinked to original sources
PubMed1970

Comparison of effect of salbutamol and isoprenaline on spirometry and blood-gas tensions in bronchial asthma.

The effect of the aerosol inhalation of 200 mug. of salbutamol and 1,000 mug. of isoprenaline on spirometry and blood-gas tensions was compared in the same 11 asthmatic subjects. Both drugs significantly reduced airway obstruction, and the extent of the reduction did not differ for periods of up to 30 minutes. After isoprenaline tachycardia and a small significant fall in arterial oxygen tension occurred, whereas after salbutamol there was no change in pulse rate and the arterial oxygen tension did not fall.

Adult↗
PubMed1969

Effect of salbutamol on spirometry and blood-gas tensions in bronchial asthma.

A new bronchodilator drug, salbutamol, reduced airway obstruction in 37 patients with bronchial asthma but did not lead to a significant fall in lowered arterial oxygen tension. This drug, unlike other bronchodilators, appears to have little or no effect on the cardiovascular system, and it is suggested that it does not therefore lead to an intensification of the ventilation/perfusion disturbance in the lung leading to a worsening of hypoxaemia.

Adult↗