PubMed Health⌕ Search

Biomedical subjects

M L Dos Santos

Publications and source records attributed to M L Dos Santos.

6 recordsLinked to original sources
PubMed1979

[Acute respiratory insufficiency associated with the ingestion of central nervous system depressants].

The study of twenty patients with poisoning by central nervous system depressant drugs is reported. The authors emphasized clinical aspects, complications and mainly the lung function impairment. Barbiturates were the most common drugs, at least in 60% of the cases, used alone or in combination with sedatives and tranquilizers. In 55% of patients the amount of the drug ingested could not be measured. In 60% of the cases we didn't know the period of time between drug ingestion by the patients and their admission to the hospital. On admisson all patients were in coma. The coma was of varying degrees and the deeper the coma the worse was lung function and complications were more frequent. Whenever a cardiovascular collapse was present there was also a high mortality rate. The authors emphasized the importance of a follow-up of these patients in intensive care units, mainly with cardiovascular and ventilatory support.

Adolescent↗
PubMed1979

[Pulmonary function in dogs submitted to bilateral cervical vagotomy (author's transl)].

A study of the effects of cervical vagotomy on pulmonary function in two groups of dogs was done: the first group had been vagotomized and submitted to spontaneous breathing and the second had been vagotomized and submitted to mechanical ventilation. pH, partial pressure of carbonic acid in arterial blood (PaCO2), partial pressure of oxygen in arterial blood (PaO2), plasmatic bicarbonate (HCO-3), alveolar arterial oxygen difference (P(A-a)O2) while the patients breathed room air and 100% O2 and pulmonary shunting didn't change after vagotomy. There was no difference between these two groups. Hemodynamic parameters like oxygen content difference (C(a-v)O2) between arterial and venous blood, heart hate (FC), mean blood pressure (Pam) and capillary hydrostatic pressure (Pcp) didn't change after vagotomy. None of these parameters were different between the two groups.

Animals↗
PubMed1979

[Anatomo-pathological alterations of the lung in hemorrhagic shock studied with lungs fixed by classical method and when expanded (author's transl)].

The authors have studied lungs of 14 dogs that have been submitted to hemorrhagic shock. The right lung was fixed in the ordinary way and the left lung in expansion. They examine preparations of a 11 lobes of both lungs. Vacuolar degeneration of the cells of the terminal bronchioles and the respiratory bronchioles, hypertrophy of the cells of the alveolar sac of mild degree were constant findings. Alveolar edema of some intensity was observed in all preparations. Atelectasias of severe degree were only seen in preparations fixed in the ordinary way.

Animals↗
PubMed1978

[Pulmonary ultrastructural changes in dogs following experimental hemorrhagic shock (author's transl)].

The authors have studied the ultrastructure of the lung in dogs following experimental hemorrhagic shock. They found intra-alveolar edema, red cells in the alveolar sac, disappearance of the substance of the lamellated osmiophilic bodies and cellular degeneration. Correlation among these alterations and increase of capillary permeability as well as consumption of surfactant secretion were established.

Animals↗
PubMed1978

[Pathological alterations in pulmonary fat embolism caused by oleic acid. Experimental study in dogs (author's transl)].

The authors studied the pathological aspects of the lungs in an experimental study made in dogs submitted to fat embolism. The histological aspects were of hemorrhagic edema when the lungs were fixed in the classical way as well when they were fixed inflated. The alveolar microatelectasias were only seen in lungs fixed in the classical way but not were seen in lungs fixed when inflated.

Animals↗