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Biomedical subjects

M L Dyken

Publications and source records attributed to M L Dyken.

At least 19 recordsLinked to original sources
PubMed1993

Overview of trends in management and prognosis of stroke.

Prevention is the ideal treatment for stroke, and the major decline in stroke mortality is most likely related to treatment of risk factors. Even when a vascular insult to the brain has occurred, an important treatment effect is the prevention of additional future events. No specific therapy for asymptomatic lesions has yet been proved to be effective. For patients with transient ischemia or mild stroke with functional recovery, the risk of additional strokes and death can be decreased by platelet-antiaggregating agents and carotid endarterectomy, which is effective in patients with greater than 70% stenosis of a symptomatic artery. Once a major stroke has occurred, the goals of therapy include prevention of disease progression, minimization of the permanent damage by the lesion, and prevention of new events. In addition to preventive therapies, several acute intervention therapies may be effective in reducing morbidity and mortality following stroke. While there are many similarities in cardiovascular and cerebrovascular disease, important differences appear to exist.

Cerebral Infarction↗
PubMed1988

Dramatic changes in the performance of endarterectomy for diseases of the extracranial arteries of the head.

Data from the National Hospital Discharge Survey have been reviewed each year to estimate the number of endarterectomies of extracranial vessels of head and neck performed in nonfederal hospitals in the United States. The number dramatically increased from 15,000 in 1971 to 107,000 in 1985. Regression estimates using data from 1971-1985 indicate that 127,000 procedures were expected for 1986, but the observed estimate indicated a dramatic drop to 83,000. Data reviewed suggest that on balance this reduction may have a favorable effect on stroke mortality and morbidity.

Carotid Arteries↗
PubMed1986

Cerebral embolism.

Explore the source record for details and available documents.

Anticoagulants↗
PubMed1982

The continuing undersupply of neurologists in the 1980s: impressions based on data from three studies.

Current unmet needs for neurologists were estimated on the basis of a survey of the directors of all academic neurology programs in the United States and Puerto Rico, by a study of the state of Indiana, and a review of potential needs by the Veterans Administration Hospitals. The number of neurologists in 1990 were predicted from residency positions filled, the membership of the American Academy of Neurology, and the AMA Master File. From these analyses, the author concludes that a shortage of from 1,214 to 5,418 neurologists may exist in 1990.

American Medical Association↗
PubMed1978

Cooperative study of hospital frequency and character of transient ischemic attacks. VIII. Risk factors.

A total of 969 (73%) of 1,328 patients with cases of suspected transient ischemic attacks (TIAs) who came to six institutions during a 21-month period were followed up. Factors were identified and prospectively analyzed for risk for further TIAs, stroke, and deatn. A history of multiple carotid artery TIAs was significantly related to further TIAs. A single TIA placed the patient at greater risk for early infarction. Older age, male sex, and unreliability to take dangerous medication were risk factors for cerebral infarction. Anticoagulant therapy, older age, male sex, diabetes mellitus, heart disease, abnormal ECG, and poor surgical risk were factors for death. The increased mortality associated with anticoagulants was confined to the older age group. While white patients treated with antiplatelet-aggregating agents had a lower mortality than those treated otherwise, this was not true amont black patients.

Age Factors↗
PubMed1978

Cooperative study of hospital frequency and character of transient ischemic attacks.

Information was collected among six participating medial centers on frequency of performance and the percentage of abnormality of 30 tests performed on patients with complaints suggesting transient ischemic attacks (TIAs). A number of these were commonly performed and commonly exhibited abnormalities. Although the diagnosis of TIA is made by history and physical examination, these tests were of value in aiding the physician to determine possible causes of TIA, to detect risk factors of associated conditions, to rule out alternative diagnoses, and to assess the patient's ability to tolerate different types of therapy.

Clinical Laboratory Techniques↗