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Biomedical subjects

M L Elson

Publications and source records attributed to M L Elson.

15 recordsLinked to original sources
PubMed1995

Soft tissue augmentation. A review.

BACKGROUND: Soft tissue augmentation is one of the most sought after cosmetic procedures around the world. It has been performed for centuries, but only in this decade or so have materials become available that allow effective therapy. OBJECTIVE: This review article discusses the use of materials for soft tissue augmentation as to where they fit into the overall scheme of treating the aging face, as well as the benefits and side effects of each, and how to maximize the use of these various materials. RESULTS: The materials reviewed with regard to both efficacy and safety of those currently on the market as well as those currently in research. CONCLUSION: With the understanding of the role of soft tissue augmentation in the overall treatment of the aging face as well as risk factors and ways to minimize the side effects, dermatologic surgeons can reach the goal of effectively treating patients with these materials.

Biocompatible Materials↗
PubMed1993

Injectable collagen and autoimmune disease.

BACKGROUND: The media and litigation in the United States have alleged a link between the use of injectable bovine collagen and the development of autoimmune disease, specifically dermatomyositis/polymyositis. OBJECTIVE: To present the scientific and epidemiologic data with regard to this issue. METHODS: Literature was reviewed as well as reports to Collagen Corporation and the litigation. RESULTS: After review of the literature and review of data currently available to Collagen Corporation, no link can be established at this time between collagen injectable material and autoimmune disease, specifically dermatomyositis/polymyositis. CONCLUSION: There are no epidemiologic or scientific data to support the alleged link in the media and litigation between injectable bovine collagen material and dermatomyositis/polymyositis.

Animals↗
PubMed1993

Dermal filler materials.

Although soft-tissue augmentation is not a new cosmetic procedure and actually has been performed for centuries, the modern era has introduced filling materials that are both safe and effective to soften the features. When used appropriately, these substances also can produce alleviation of scars and even true augmentation of the face. Newer techniques are being developed to access extremely fine lines, especially around the eyes. As research continues into newer materials, more procedures will become available and be more accessible to physicians and patients as the search for the perfect material for soft-tissue augmentation continues.

Biocompatible Materials↗
PubMed1992

Soft tissue augmentation of periorbital fine lines and the orbital groove with Zyderm-I and fine-gauge needles.

A new procedure utilizing Zyderm-I (Collagen Biomedical, Palo Alto, CA) and a 32-gauge needle for augmentation of the periorbital fine lines and the orbital groove is described. This advanced soft tissue augmentation technique is described in detail in 30 patients with before, after, and 1-week post-augmentation photographs presented by the author. This technique requires familiarity with soft tissue augmentation and the use of collagen injectable materials as well as specific training on a one-to-one basis with someone experienced with this particular technique.

Adult↗
PubMed1990

Treatment of striae distensae with topical tretinoin.

The experience of 20 patients with striae distensae of varying etiologies and the treatment with topical tretinoin is described. Of the 16 patients who completed the study, 15 had significant improvement in their clinical picture.

Administration, Cutaneous↗
PubMed1989

The role of skin testing in the use of collagen injectable materials.

The experience of 400 consecutive patients evaluated for soft tissue augmentation for a variety of contour defects is reviewed here. The first 200 patients were evaluated with only a single skin test prior to treatment, whereas the second group were skin tested twice. The rate of hypersensitivity to the first skin test was the same in both groups, 5 out of 200 (2.5%). In the 195 patients receiving treatment after a single negative skin test, 6 (3.1%) developed hypersensitivity reaction at treatment sites. In the second group, where double skin testing was employed, an additional 7 patients had a positive second skin test (3.5%). There were no allergic reactions in the 171 patients who received treatment after two negative skin tests.

Adult↗
PubMed1988

Clinical assessment of Zyplast Implant: a year of experience for soft tissue contour correction.

The advent of injectable collagen for soft tissue augmentation has opened an entirely new area for the dermatologic cosmetic surgeon and for dermatologists who have a particular interest in the cosmetic aspect of our specialty. Patient demand for correction of soft tissue contour irregularities is high and continues to increase daily. The use of injectable collagen with appropriate technique can provide these patients with significant improvement without great cost or significant side effects. In the year following the introduction of glutaraldehyde cross-linked Zyplast Implant, 188 patients were evaluated for soft tissue augmentation with bovine collagen in my clinical practice. Diagnoses varied from facial elastosis to scars due to acne, pox, trauma, and cancer. Some patients desired changes in facial contour (thicker lips; postrhinoplasty defect). Patient satisfaction was high (83% good or excellent results) and side effects were minimal. In our study we found that 3% of patients demonstrated hypersensitivity to the test implant. Treatment with non-cross-linked Zyderm and Zyplast collagens in the patients with a negative skin test resulted in six hypersensitivity reactions (3%). In these patients reactions were not observed at sites treated only with cross-linked collagen and clinical responses appeared to be directed at the non-cross-linked collagen implant sites. With proper treatment technique and patient consultation, the results obtained with injectable collagen fulfill expectations of treated patients.

Adolescent↗
PubMedDate not supplied

Use of tretinoin in female health practice.

Tretinoin (all trans-retinoic acid) is extensively used in the treatment of acne as Retin-A; of photoaging as Renova; and in the treatment of striae distensae. The indications, rationale, and clinical observations are discussed in detail so that these may be instituted in the practice of female health.

Acne Vulgaris↗