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Biomedical subjects

M L Fedorova

Publications and source records attributed to M L Fedorova.

At least 19 recordsLinked to original sources
PubMed1979

[Neurologic manifestations of periodic disease].

Results of comprehensive neurological examinations of 4 patients suffering from periodic disease have shown that the latter may be not only a disease entity, but also a syndrome characterizing some organic affections of the brain. The abdominal and other crises of the periodic disease included cerebrovascular disturbances which manifested hemipareses, syncopes, and migraine-like cephalgia. EEG and REG examinations have revealed dysfunction of the mesodiencephalic structures which, probably, underlies the pathogenesis of the periodic disease. The knowledge of the formerly almost unexplored neurological manifestations of the periodic disease will contribute to improvement of the therapy of this rare ailment.

Abdomen↗
PubMed1979

[Features of the course of psoriasis in patients with organic diseases of the nervous system].

Of 190 patients suffering from psoriasis in 65 (34.2%) hypothalamic syndrome, sequelae of neuroinfections and craniocerebral injuries, acute and chronic insufficiency of cerebral circulation were noted. These diseases preceded the development of psoriasis in 22.6% of the patients, the fact, that gives one grounds to regard them with a greater probability as a pathogenetic factor of psoriasis. In the patients suffering from psoriasis and the above diseases of the nervous system an inclinication to exudative and pustulous manifestations, arthropathy, and erythroderma, as well as frequent resistance to the therapy and torpid course of the disease were observed. An exacerbation of psoriasis aggravated some neurological disorders, and a deterioration of the neurological state coincided in time in some patients with exacerbation of psoriasis. The interaction between the dermal and the neurological disturbances appeared to be a reason for supplementing the complex of measures for psoriasis treatment with means improving the metabolic processes in the brain, psychotropic and vasocative drugs, and diadynamic currents that produce normalizing effects on the vegetative functions and cerebral hemodynamics.

Adolescent↗
PubMed1978

[Loss of consciousness in migraine].

The author conducted a clinico-electrophysiological study of 350 patients with migraine. In 12.5% of the patients there were cases with a loss of consciousness. The conclusion is made that in combination of one attack of symptoms of migraine and epilepsy they have one pathogenesis: vasomotor disorders evoking both migrainose crises and syncopes with a convulsive syndrome. Quite typical of such conditions are precursors, massive vegetative disturbances, a tonic character of the convulsions. A loss of consciousness in the intra-attack period may be assessed as a syncope, mainly of orthostatic and vaso-vagal type; a loss of consciousness during the attack--as a syncope connected with migrainose disorders of cerebral hemodynamics. In alternation of migrainose and epileptical attacks it is claimed that there is a combination of 2 diseases. The conclusion is made that a loss of consciousness in migraine and epilepsy are different not only by clinical signs, but by its pathogenesis. This fact determines the preventive therapy of both diseases.

Adolescent↗
PubMed1976

[State of the nervous system in psoriasis patients].

In order to clarify the role of the nervous system in the development of psoriasis the authors conducted a manifold dermato-neurological, biochemical and electrophysiological (EEG, REG) study of 130 patients. In 76.4% there were different neurological disorders: vegetative-vascular disturbances, functional diseases of the nervous system. Psoriasis was also seen in combination with segulae of brain injuries, neuroinfections, hypothalamic syndrome, vascular brain lesions, epilepsy. Clinico-electrophysiological studies detected a dysfunction on all levels of the brain, mainly in the limbico-reticular complex and mesodiencephalic formation. Quite possibly the above-mentioned changes are of significance for the development of psoriasis, making the use of drugs influencing these brain structure necessary. Taking into consideration the REG data it is also necessary to use preparations influencing the vascular tone of the brain and physiotherapeutical procedures normalizing the cerebral hemodynamics.

Adolescent↗