PubMed Health⌕ Search

Biomedical subjects

M L Goodman

Publications and source records attributed to M L Goodman.

88 records · Page 5Linked to original sources

Meningiomas presenting in the paranasal sinuses and temporal bone.

Head and neck meningiomas are primarily intracranial neoplasms; they rarely present in extracranial locations. Two cases of meningiomas in the paranasal sinuses and seven cases in the temporal bone are described. The pathology, pathogenesis, clinical evaluation, and therapy are discussed. It is stressed that intracranial components of such meningiomas be sought and, as appropriate, treated.

Aged↗

Desmoplastic squamous cell carcinoma of the tongue simulating myositis or fasciitis.

An unusual form of squamous cell carcinoma of the tongue is reported, the "de novo" submucosal evolution of which is unique. Histologic definition of this malignancy and its distinction from clinically similar benign and malignant conditions are detailed through a brief review of the relevant differential diagnoses. The importance of circumspect diagnostic reassessment when the clinical behavior of a lesion contradicts apparent histologic benignancy is emphasized and treatment inferences are drawn.

Adult↗

Angiosarcoma of the carotid artery: a case report.

Angiosarcomas are rare tumors, particularly in the head and neck region. A case report of an angiosarcoma arising in the internal carotid artery is described; such an occurrence has not previously been reported. The etiology, pathology, and treatment of this unusual tumor are discussed.

Carotid Artery Diseases↗

Hodgkin's disease of the nasopharynx.

Malignant lymphoma of the Hodgkin's disease type involving the nasopharynx has been considered a rare entity. However, recent publications suggest that such involvement may not be uncommon. The authors describe their experience with two patients with histologically proven involvement of the nasopharynx by Hodgkin's disease. The diagnosis is difficult to establish. Histologic confirmation may require persistence and necessitates close cooperation with the pathologist. The prognostic significance of Hodgkin's disease involvement of the nasopharynx remains unknown. The otolaryngologist should be aware of these issues and be available to assist in the evaluation of the patient with lymphoma.

Hodgkin Disease↗

Follicular carcinoma of Hürthle cell type as cause of hemoptysis.

Summary--A patient with follicular carcinoma, Hürthle cell type, who developed subglottic extension and uncontrollable hemoptysis is presented . In consideration of the patient's age a conservative therapeutic program was instituted with a definite response to I-131 therapy despite poor radioactive iodine (RAI) uptake by the tumor. Laryngectomy and thyroidectomy were eventually required to control hemoptysis; the patient remains socially functional and asymptomatic after a 30-month period. The two-year period of weekly office visits and temporizing treatment as occurred in this patient cannot be recommended. It seems appropriate to advocate surgical treatment including laryngectomy for follicular carcinoma, Hürthle cell type, localized to the laryngotracheal area without regard for the age of the patient.

Adenocarcinoma↗

Upper airway obstruction associated with regional enteritis.

Two patients are presented with upper airway obstruction associated with regional enteritis (Crohn's disease). Two mechanisms for this obstruction are proposed. The first is involvement of the cricoarytenoid joint with the inflammatory process and the second is extensive edema of the upper airway due to submucosal involvement with the disease process. We were unable to find any previous reports of upper airway obstruction associated with regional enteritis. The data from these patients suggests that Crohn's disease should be included in the differential diagnosis of chronic persistent laryngeal edema.

Adult↗

Rheumatoid cricoarytenoid arthritis complicated by upper esophageal ulcerations.

Arthritis of the laryngeal joints occurs with most of the diseases which are manifest by polyarthritis. This publication discusses an unusual extension or complication of cricoarytenoid arthritis, ulcerative necrosis of the postcricoid cervical esophagus which necessitated a total laryngectomy in a patient with advanced rheumatoid arthritis.

Arthritis, Rheumatoid↗

Nasopharyngeal masses in adults.

Nasopharyngeal masses in adults present a perplexing problem because of the concern for malignancy. A retrospective review of the records, radiographs and biopsy histology of 57 patients presenting in one year with nasopharyngeal masses at the Massachusetts Eye and Ear Infirmary suggests that persistent pain, epistaxis, trismus, or cervical mass are uncommon in patients with benign histology and should alert the clinician to the probability of malignancy. A high index of suspicion on the part of the clinician is essential for the successful recognition of early lesions. The roles of conventional radiography, polytomography, and computed tomography scans are discussed. Patients with malignant lesions are contrasted with those having benign lesions.

Adult↗

Cholesterol granuloma of the petrous apex: MR and CT evaluation.

We reviewed the clinical, CT, and MR findings in seven consecutive patients who had a total of nine cholesterol granulomas. Preoperative MR scans were available for five of the seven patients; two patients were studied with MR after treatment only (one had a recurrent lesion and the other was asymptomatic at the time of study). Preoperative CT scans were available for all patients, except one patient who was examined after developing a symptomatic recurrence. All lesions were detected by both imaging methods. Seven preoperative lesions (five patients) and one symptomatic recurrence (one patient) demonstrated increased signal intensity of both T1- and T2-weighted MR images. Three surgically drained lesions (three patients) showed a marked reduction in signal intensity on T1-weighted images. Pre- and postoperative lesions had different patterns of signal intensity on the chemical-shift images, which were obtained in two instances. The MR appearance of cholesterol granuloma differs from that of most other lesions that occur in the petrous apex. CT did not differentiate between pre- and postoperative lesions in all cases, while MR demonstrated a dramatic change on T1-weighted images and chemical-shift studies. Our findings indicate that MR is more specific than CT in suggesting the correct diagnosis of cholesterol granuloma and that MR appears to be the technique of choice in the follow-up of previously treated patients.

Adult↗