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Biomedical subjects

M L Kulkarni

Publications and source records attributed to M L Kulkarni.

At least 73 records · Page 4Linked to original sources
PubMed1991

Amniotic band syndrome (ABS): report of a case.

Amniotic band syndrome (ABS) is a rare collection of malformations associated with thread-like strands connecting the amnion and any part of the fetus. A case is reported where the constriction rings and amputation of fingers and the cleft lip/cleft palate constituted the main features of this syndrome.

Amniotic Band Syndrome↗
PubMed1990

Consanguinity and its effect on fetal growth and development: a south Indian study.

The effect of consanguinity on fetal growth and development was studied in 3700 consecutive births (live and stillborn); 26% of the total births were to consanguineous couples. Hindus had a higher frequency of consanguineous marriages, uncle-niece unions being the commonest type, whereas Moslems preferred first cousin marriages. The incidence of congenital malformations was 39.1/1000 births with a significantly higher incidence among the consanguineous group (8.01%) as against the nonconsanguineous group (2.42%) (p less than 0.001). The incidence of malformations was higher in the uncle-niece matings (9.34%) compared to the first cousin marriages (6.18%) (p less than 0.01). Malformations of major systems were significantly more frequent among the consanguineous couples, whereas malformations of the eyes, ears, and skin did not show any significant effect of consanguinity. Stillbirth rates were significantly higher in the consanguineous group, irrespective of the mother's socioeconomic status, and were higher in uncle-niece matings compared to first cousin and beyond first cousin unions in both the poor and middle/upper class. A significant decrease in the mean birth weight and head circumference of babies born to consanguineous parents was noted in both the poor and middle/upper socioeconomic class. The mean length was less in babies born to consanguineous parents belonging to the poor social class only.

Abnormalities, Multiple↗
PubMed1989

The range of neural tube defects in southern India.

During a prospective study of 3500 consecutive births from November 1985 to January 1987 at three hospitals, 40 babies were found to have neural tube defects, an extremely high incidence (11.4/1000 births). The defects comprised anencephaly (n = 18), meningomyelocele (n = 11), Arnold-Chiari deformity (n = 3), encephalocele (n = 3), iniencephaly (n = 2), and one each of occipital meningocele, spina bifida occulta, and anencephaly with rachischisis. There were significant differences in incidence between those with consanguineous and nonconsanguineous parents and those whose mothers had previously given birth to malformed infants or who had had miscarriages, and those who had not. Significantly more defects were found among stillborn and low birthweight babies, among girls, and among those whose mothers were aged between 20 and 30 years. Just over a third (14) were breech presentations, and hydramnios was present in 16 (40%).

Abnormalities, Multiple↗