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Biomedical subjects

M L Lecklitner

Publications and source records attributed to M L Lecklitner.

At least 19 recordsLinked to original sources

Musculoskeletal findings in Klippel-Trenaunay syndrome.

Klippel-Trenaunay syndrome is an angio-osteohypertrophy syndrome without deep arteriovenous malformations. Clinical manifestations consist of vascular nevi, varices, and bony and soft-tissue hypertrophy. On skeletal imaging, there was extensive radionuclide uptake in a massively enlarged right lower extremity.

Bone and Bones↗

Bone imaging in the assessment of en bloc osteocutaneous autotransplantation.

A patient is presented who sustained an avulsed portion of the mandible and all soft tissues of the floor of the oral cavity, requiring an autogenous en bloc transplant to replace the avulsed tissues. The clinical role of bone imaging in assessing the patency of the microvasculature and viability of the vascularized osteocutaneous graft is discussed, and the criticality of the time of image acquisition in prognosticating the success of the transplantation is emphasized.

Adult↗

Gallium-67 and pulmonary complications of amiodarone.

A 66-year-old white man with amiodarone pneumonitis is presented. The diagnosis was made with the aid of Ga-67 imaging, which is a sensitive method of detecting amiodarone pulmonary toxicity in patients with symptomatic pulmonary infiltrates on chest radiographs. Ga-67 imaging is especially useful in distinguishing amiodarone pneumonitis from congestive heart failure.

Aged↗

Increased extremity uptake on three-phase bone scans caused by peripherally induced ischemia prior to injection.

During arterial flow scintigraphy, increased tracer uptake in the upper extremity has been noted secondary to induced ischemia distal to blood-pressure cuffs and simple tourniquets, employed prior to the injection. We prospectively studied 68 patients undergoing three-phase bone scintigraphy to evaluate the frequency and magnitude of this artifact. The results showed that when a blood-pressure cuff was applied virtually all patients demonstrated increased activity in the extremity of cuff application. When a simple rubber tourniquet was applied few patients demonstrated the artifact. Only one patient, a case of reflex sympathetic dystrophy syndrome, had increased uptake on blood-pool and skeletal-phase images. We recommend that in flow studies of the hands, wrists, and forearms, blood pressure cuffs not be employed and that at least 3 min should elapse between release of the occlusive device and injection. Asymmetry of flow under these conditions is unlikely to be artifact.

Blood Pressure Determination↗

Osteoscintigraphy and brachydactylia of the hand.

Few reports have addressed scintigraphic abnormalities in the configuration of the hands. The purpose of this report is to present a case of congenital brachydactylia of the hands and to emphasize both acquired and projectional scintigraphic findings of brachydactylia.

Female↗

Positive predictive value of cholescintigraphy in common bile duct obstruction.

Technetium-99m DISIDA imaging was employed in 400 patients to differentiate obstruction of the common bile duct from medical and other surgical causes of hyperbilirubinemia. Sequential anterior images demonstrated variable degrees of liver uptake, yet there was no evidence of intrabiliary or extrabiliary radioactivity for at least 4 hr after injection in 25 patients. Twenty-three patients were surgically documented to have complete obstruction of the common bile duct. One patient had hepatitis, and another had sickle cell crisis without bile duct obstruction. The remaining patients had either partial or no obstruction of the common bile duct. We conclude that the presence of liver uptake without evident biliary excretion by 4 hr on cholescintigraphy is highly sensitive and predictive of total obstruction of the common bile duct.

Adult↗

Hepatic cavernous hemangioma: a potential pitfall during evaluation of gastrointestinal bleeding with 99mTc-labeled erythrocytes.

The purpose of this report is to underscore one previously unreported hepatic parenchymal lesion detected during evaluation of occult lower gastrointestinal hemorrhage. In more than 90% of the patients harboring the lesion, the individual remains asymptomatic, requires no intervention, and closed biopsy is contraindicated: hepatic cavernous hemangioma. Whereas the list is expanding of normal and abnormal structures which can interfere with the interpretation of scintigraphic gastrointestinal bleeding studies accomplished with 99mTc-labeled erythrocytes, it is absolutely necessary to demonstrate intestinal transit of the activity, in order to discount detected activity in either nonhemorrhagic lesions or normal structures as the nidus of suspected bleeding.

Erythrocytes↗

Hepatic amebic abscess masquerading as acute cholecystitis.

Hepatobiliary scintigraphy has disclosed a host of intrahepatic and extrahepatic lesions which mimic gallbladder disease. Two cases of hepatic amebic abscess are reported in which the presentations masqueraded as acute cholecystitis. Correlative, noninvasive imaging rapidly diagnosed both cases and in 1 case identified a serious complication.

Adolescent↗