PubMed Health⌕ Search

Biomedical subjects

M L Loiseau-Marolleau

Publications and source records attributed to M L Loiseau-Marolleau.

13 recordsLinked to original sources
PubMed1977

[Pseudomonas putida: identification, antibiotic sensitivity and pathogenicity (author's transl)].

This work studies 51 strains of Pseudomonas putida, isolated from clinical specimens (17) and hospital environment (34). Identification is performed by study of 41 physiologica and biochemical characters and 78 nutritional characters. According to the two biotypes A and B, described by Stanier, Palleroni and Doudoroff, these 51 strains can be grouped as follows: 48 have typical characters of biotype A, widely predominant, 3 can be distinguished from biotype A only by their auxanogram and included in biotype B. Antibiogram pattern of P. putida shows two salient features: resistant to carbenicillin and sensitivity to kanamycin. Among 17 human isolates, only 4 have likely pathogenic significance. By intraperitoneal challenge in mice, one half of strains is avirulent, other strains have a very low virulence (LD50: from 2,2 to 5 X 10(8) viable cells). There is no relationship between experimental virulence and bacterial sources.

Animals↗
PubMed1977

[Virulence of human and environmental strains of "pseudomonas aeruginosa" in mice (author's transl)].

The virulence of 21 clinical isolates and 10 environmental strains of Pseudomonas aeruginosa was studied by intraperitoneal challenge in mice. The LD50 values of human strains ranged from 10(7),(0) to 10(8),(5) viable cells per mouse (average: 10(7),(7)(2)). The LD50 of environmental strains ranged from 10(7),(2) to 10(8),(1) (average: 10(7),(59)). These results are not significantly different. Experimental virulence for mice of P. aeruginosa strains found in hospital environment allows no prediction on their level of pathogenicity for in-patients. Furthermore, this study proved no relationship between letal effect of P. aeruginosa for mice and following characters of strains: O serogroup, untypability and productivity of specific pigments, pyocyanin and pyorubrin.

Animals↗