The Mobetron: a new concept for IORT.
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Biomedical subjects
Publications and source records attributed to M L Meurk.
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(1) 50 consecutive patients with cancer of the prostate, stages A2 through C2 received external irradiation. The whole pelvis was treated using 4-MV photons, and a prostate boost was given through the perineum using a cesium-137 teletherapy unit. (2) The treatment technique was easily duplicated daily and was well tolerated. There were no grade 2, 3 or 4 complications. (3) Local control was excellent: 96% of all cases. (4) Disease-free survival was high. (5) Potency was maintained in the majority of this elderly population. Considering that American males have an increasing longevity and thus a greater likelihood of developing cancer of the prostate, external-beam radiation therapy should be utilized in the future even more so than today. We must continue to refine radiation therapy techniques in order to further increase disease-free survival and reduce radiation morbidity.
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A study comparing the RBE in depth of 23-MeV electrons was performed. A mouse sarcoma (KHT) maintained by serial passage in the C3H/HeJ female mouse was irradiated. Under the 23-MeV electron beam at the 100-percent and 14-percent isodose positions and under the 60Co beam at the 100-percent isodose position. The data failed to demonstrate a difference in biological effectiveness for the 23-MeV electron beam comparing the 14-percent isodose to the 100-percent isodose position.
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