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Biomedical subjects

M L Morris

Publications and source records attributed to M L Morris.

At least 37 records · Page 2Linked to original sources
PubMed1984

Treatment and prevention of feline struvite urolithiasis.

A diet providing less than 20 mg of magnesium per 100 kcal that maintains urine pH near 6.0 3 to 5 hours after eating, or a diet providing this amount fo magnesium (see Table 2) with 1 gm of ammonium chloride or 1.5 gm of dl-methionine added daily, should be fed for 1 to 3 months to dissolve struvite uroliths (see Fig. 1). The low-magnesium diet should be fed indefinitely to prevent recurrence, because struvite urolithiasis and all of its effects (hematuria, pollakiuria, and/or complete to partial obstruction to urinary excretion) recurs repeatedly in cats that have previously experienced the condition if they are returned to regular cat food. In contrast, if a diet low in magnesium is fed, recurrence is uncommon. For cats that have never been affected, feeding a low-magnesium ration is unnecessary. For all cats, the following measures are recommended: encourage exercise, allow frequent urination, prevent obesity, decrease confinement, keep the litter box clean, and always have palatable water readily available.

Animal Feed↗
PubMed1984

Canine urolithiasis: diagnosis and treatment.

Over 97% of all uroliths in males less than a year of age and in females are phosphate, excluding males with portosystemic shunts and male Dalmatians . Uroliths in male Dalmatians usually are composed of urate. Uroliths associated with Staphylococcus aureus urinary tract infection are phosphate. About 60% of uroliths in adult male Basset Hounds , Bulldogs , Chihuahuas , Irish Terriers and Yorkshire Terriers are cystine. In males of other breeds, as high as 60% of uroliths are phosphate. Feeding a calculolytic diet (s/d: Hill's) results in phosphate urolith dissolution in 2-20 weeks. Long-term feeding of the calculolytic diet is not recommended, nor is use after surgery and in pregnant, lactating or growing dogs and in those with heart failure, edema, ascites or pleural effusions. Uroliths recur in 20-50% of affected dogs without subsequent dietary alteration. Use of a urolith-prevention diet (u/d: Hill's) is recommended if urolithiasis recurs.

Animals↗
PubMed1981

The effect of marrow on the formation of "functionally" oriented collagen fibers.

It has been shown that "functionally" oriented collagen fibers will attach to cementum when a healthy root fragment is implanted subcutaneously along with decalcified autogenous bone. The purpose of the present study was to test the effect of a strong bone grower (marrow) on this inductive system. Twenty-six composite grafts of healthy root, decalcified autogenous bone and marrow were implanted in thirteen 200 gm, female, white, Sherman-strain rats. Sixteen composite grafts without roots were similarly implanted, as controls, into eight animals. Postoperative periods ranged from 1 week to 8 months. With the exception of one section, the results showed that the addition of marrow prevented the formation of "functionally" oriented fibers. It is further evidence that strong bone formers do not produce a periodontium.

Animals↗
PubMed1980

A new hypothesis of periodontal homeostasis.

A review of the experimental evidence evidence on marrow inhibition by implanted roots has shown that an inhibitory factor is present in all root surfaces. It is most marked in periodontally diseased roots and least in periodontally healthy roots. It is hypothesized that a "marked" amount would inhibit periodontal cells to the point where they could not resist the destructive effects of plaque, calculus and bacteria. A lesser or "moderate" amount would result in a more resistant periodontium. Finally, little or no inhibitor would also create a periodontium resistant to periodontal destruction but at the same time would remove restraints on the alveolar bone; the result would be invasion of the periodontal space and ankylosis to the root.

Alveolar Process↗
PubMed1980

The effect of root decalcification on the formation of "functionally" oriented collagen fibers.

It has been shown that "functionally" oriented collagen fibers will attach to cementum when a healthy root fragment is implanted subcutaneously in the rat along with decalcified autogenous bone. The purpose of the present study was to show how prior root decalcification affected this inductive action. Twenty-six pairs of bone and root were implanted in 13 200-gm, female, white, Sherman strain rats. The postoperative periods ranged from 1 week to 12 months. The results showed that root decalcification prevented formation of the "functionally" oriented fibers and inhibited bone induction by the decalcified autogenous bone. It was suggested that all roots have an inhibitor, the least amount in periodontally healthy roots and the most in periodontally diseased roots. It was suggested that the clinical successes in reattachment reported with acid treatment of roots were due to the denaturant effects rather than surface decalcification.

Animals↗
PubMed1978

The effects of root shape and biology on bone growth.

A statistical study was carried out on the influence of root surfaces on adjacent cellular activity. This activity is indeed affected by both the shape and the biology of those surfaces. Flat surfaces tend to inhibit, nicked surfaces tend to stimulate bone formation in a bone-growing environment. A biologic effect is exerted by the matrix of diseases roots. They contain an inhibitory principle which is not present in healthy roots. This factor is masked by the apatite structure and is destroyed by heat.

Animals↗
PubMed1978

The submucosal implantation of human allogeneic decalcified dentin.

Decalcified human dentin was implanted into the buccal oral mucosa of 10 human volunteers and was later recovered for histologic examination. Extensive resorption took place. Bone did not form. Human dentinal matrix is not a bone inducer. Differences between the two methods of decalcification were not relevant.

Adult↗