Developing eye in an ovarian teratoma.
A malignant teratoma of the ovary was resected in a 14-year-old girl. Within the tumor, a partially developed eye was found.
Biomedical subjects
Publications and source records attributed to M L Mund.
A malignant teratoma of the ovary was resected in a 14-year-old girl. Within the tumor, a partially developed eye was found.
Corneal deposits of granular dystrophy were studies in six corneas from five patients. Two additional corneas from two patients with lattice dystrophy were used for comparison. The diagnoses were confirmed by light and electron microscopy. Three types of ultrastructural features were distinguished in the electron-dense rod-shaped deposits of granular dystrophy, i.e., Type 1 with homogenous structure, Type 2 with fibrillar constituents, and Type 3 with a moth-eaten or sponge-like appearance. In polarization microscopy of Congo-red stained sections, the Type 2 tended to show an increased birefringence without green dichroism, while the other types were less birefringent than the stroma. Three different components were found immediately around the deposits, i.e., 1. normal collagen fibrils, 2. finely filamentous substance, and 3. areas of thin fibrils (70-100 A in diameter). While the second component appeared non-specific, the third component was found only in two corneas, superimposed on the lesions of granular dystrophy, and showed light and electron microscopic characteristics of the lesions of amyloid as well as of lattice dystrophy.
Four full-thickness corneal buttons and tissue from one lamellar keratoplasty, derived from four patients with granular corneal dystrophy recurring in previously transplanted corneas, were studied by light and transmission electron microscopy. Fibrous tissue without vascularization was present between the epithelium and Bowman's membrane and contained deposits characteristic of granular dystrophy in both light and electron microscopy. The recurrence of dystrophy in the normal donor cornea is the result of infiltration of the grafted cornea by host invasion. The donor stroma is spared.
A four-year survey of all ocular trauma cases admitted to a large metropolitan eye hospital was conducted for the purpose of generally documenting ocular trauma and evaluating prophylactic, demographic and etiologic factors. Of 6254 eye admissions, 7.5% were for ocular trauma; hyphema was the most common diagnosis. Injuries were evaluated according to site, cause, and age, sex and race distribution.