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Biomedical subjects

M L Prasad

Publications and source records attributed to M L Prasad.

60 records · Page 4Linked to original sources
PubMed1982

Bacteremia associated with lower gastrointestinal endoscopy, fact or fiction? I. Colonoscopy.

A survey of the medical literature reveals conflicting data as to whether bacteremia occurs during endoscopic examination of the lower gastrointestinal tract. In an attempt to study this problem a prospective study was undertaken, and the first arm of the study included patients undergoing colonoscopy. The second arm of the study, comprising patients undergoing proctosigmoidoscopy, will be presented subsequently. Fifty-one patients undergoing colonoscopy were studied. Excluded from the study were patients with elevation of temperature above 101 degrees F, inflammatory bowel disease, diarrhea, valvular heart disease, vascular prosthesis, chemotherapy, or immunosuppression. Aerobic and anaerobic culture were done before and after the procedure, as well as at timed intervals during the procedure. Whenever biopsy or polypectomy were carried out, further cultures were done. Skin cultures were done from venipuncture sites. In one patient (2 per cent) Staphylococcus epidermidis was found in more than one set of cultures. Polypectomy or biopsy were not associated with bacteremia.

Colonoscopy↗
PubMed1981

Supralevator abscess: diagnosis and treatment.

Anorectal suppurations are quite common. Supralevator abscesses, previously regarded as a rare subgroup, were seen in 9.1 per cent of 506 patients admitted to Cook County Hospital in a two-year period. Aggressive supportive management was followed by early, adequate drainage through the rectum whenever indicated. When fistulas were identified, either a primary fistulotomy or a two-stage fistulotomy using a seton was performed in the majority of cases. Important factors in the prevention of morbidity and mortality included debridement of all necrotic tissue, careful bacteriologic studies and judicious use of antibiotics, close postoperative observation, and long-term follow-up of the patients.

Abscess↗
PubMed1980

Malignant potential of perianal condyloma acuminatum.

Perianal condyloma is usually a benign disease, but may become locally aggressive; carcinomatous change may occur. This disease could be potentially malignant, and if malignant transformation occurs the treatment should include abdominoperineal resection. Perianal condylomas in association with anal fistula show malignant behavior; should such malignant behavior develop in perianal condyloma, the disease should be treated aggressively with excision and immunotherapy. Abdominoperineal resection may be necessary.

Adult↗
PubMedDate not supplied

Iatrogenic perforation of the colon and rectum.

In eight years at Cook County Hospital, 42,000 barium enemas, 16,325 proctosigmoidoscopies, and 1207 colonoscopies were performed. All endoscopic procedures were done by the house staff. There were three perforations due to proctosigmoidoscopy, with one death; three perforations due to colonoscopy, with no deaths; and seven perforations due to barium enema, with no survivors. The adjuvant effect of barium sulfate is proposed as the most likely cause for this excessively high mortality in barium-enema perforation.

Aged↗