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Biomedical subjects

M L Suri

Publications and source records attributed to M L Suri.

12 recordsLinked to original sources
PubMed1992

Cryptogenic osteomyelitis of the skull and intracerebral abscess.

The authors report a rare case of cryptogenic osteomyelitis of the skull with an intracerebral and a subgaleal abscess. Total excision of the abscess extending from the cortical surface to the lateral ventricle led to ventriculitis and subgaleal cerebrospinal fluid collection. These complications could have been avoided by aspirating the abscess after removing the infected portion of the skull and the epidural granulation tissue. Neurosurgeons preferring to excise such an abscess should leave a small area of capsule at the base in order to avoid having to open the ventricle.

Brain Abscess↗
PubMed1978

Platelet adhesiveness, plasma fibrinogen, and fibrinolytic activity in young patients with ischaemic stroke.

Cerebral thromboembolic stroke in the young is uncommon. Disturbances in the n ormally existing dynamic equilibrium between coagulation and fibrinolysis may play a major role in the pathogenesis of such episodes. In a search for a possible hypercoagulable state platelet adhesiveness by the method of Eastham, plasma fibrinogen and euglobulin clot lysis times were estimated in 46 patients. A group of 15 normal subjects matched for age and sex were also studied for comparison. Significant increase in platelet adhesiveness (P less than 0.001) and plasma fibrinogen (P less than 0.001) was noted in the patients when compared with the normal subjects. Absence of corresponding increases in fibrinolytic activity in the patients suggests disturbed equilibrium between coagulation and fibrinolysis. The possibility of a hypercoagulable state in these cases is discussed.

Adult↗
PubMed1978

Changes in EEG pattern during acclimatization to high altitude (3500 m) in man.

This study was conducted on 30 healthy soldiers to observe EEG changes during acclimatization to high altitude. Of these subjects, 10 were lowlanders (LL), 10 were acclimatized low landers (AL), and 10 10 were high-altitude natives (HAN). The EEG was recorded by the 10-20 international system of electrode placement in LL at sea level (SL) during rest and hyperventilation (HV). Then they were air-lifted to an altitude of 3500 m where periodic recordings of EEG were made for 4 weeks. For comparison, the altitude recordings were also made in AL and HAN. The quantitative analysis of EEG (occipital) was done to determine alpha index (AI) and average amplitude. The mean AI was 25.5% at SL in LL, which changed to 45.7%, 15.8%, 28.0%, 30.3%, and 33.2% on days 2, 7, 14, 21, and 28, respectively. The average amplitude was 17.3 microV at SL, which changed to 23.3 microV, 11.8 microV, 16.2 microV, 17.3 microV, and 19.8 microV on days 2, 7, 14, 21, and 28, respectively. In two subjects, spiking was seen along with the desynchronized pattern of EEG on days 7 and 14. The AI and average amplitude of AL and HAN were significantly more than those of LL. The magnitude of buildup during HV was greater at altitude. These results indicate that there is cerebral cortical depression in the initial phase of induction which changes to cortical desyncronization in the latter part of the first week of induction. During acclimatization, there is gradual buildup of EEG waves, as observed in AL and HAN.

Acclimatization↗
PubMed1977

Electroencephalographic studies with i.v. methaqualone in man.

Methaqualone injected i.v. has been reported to be a safe short-acting anaesthetic agent and a muscle relaxant in man. It has been employed in a variety of operative procedures and to modify convulsions in the management of tetanus and in electroconvulsive therapy. Safety, usefulness and the marked central effects of the drug led us to study its central effects by EEG in man. Discrepancies between clinical and EEG signs were thus seen. EEG patterns resembled those after barbiturates and the effect was dose dependent. Differences between methaqualone and barbiturates are discussed. The EEG patterns were potentiated by thioridazine and antagonised by imipramine.

Adult↗
PubMed1977

Platelet adhesiveness in young patients with ischaemic stroke.

A significant increase in platelet adhesiveness was observed in 13 patients who developed ischaemic stroke at high altitude and in 43 patients who developed stroke at low altitude when compared with a similar group of normal healthy volunteers. Eighty-eight percent of the patients were below the age of 40 years. The role of platelet adhesiveness in the pathogenesis of cerebral schaemia in young patients is discussed.

Adolescent↗
PubMed1977

Neurological and related manifestations of cysticercosis.

Neurological and related manifestations of 17 cases of human cysticercosis have been reported. The cases have been grouped into convulsive disorder (6 cases), meningo-encephalitis (4 cases), pseudo-tumour syndrome (2 cases), psychiatric disease (2 cases), ocular cysticercosis (2 cases) and pseudomuscular hypertrophy (1 case) which proves the varied clinical manifestations of the disease.

Adolescent↗