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Biomedical subjects

M Lüchtenberg

Publications and source records attributed to M Lüchtenberg.

9 recordsLinked to original sources
PubMed2000

[Intraocular pressure response after administration of 3 different viscoelastic agents after cataract operation].

UNLABELLED: By using three different viscoelastics [Adatocel (methylhydroxypropylcellulose), Amvisc Plus (sodium hyaluronate) and Healon (sodium hyaluronate)] a prospective randomized study was conducted to investigate whether postoperative intraocular pressure shows significant differences according to the viscoelastics used after 150 cases of cataract surgery. PATIENTS AND METHODS: The inclusion criteria for this study were: extracapsular cataract extraction via the usual small-incision techniques and endocapsular posterior-chamber lens implantation. A total of 150 eyes were operated upon. The patients were randomly assigned to three groups according to the viscoelastics, 50 cases used adatocel, 50 Amvisc Plus and 50 Healon. As far as possible, the viscoelastics were sucked out under visual control. Intraocular pressure (IOP) was measured after 6 and 24 h. RESULTS: Six hours postoperatively, no statistically significant difference between the intraocular pressure after using different viscoelastics (adatocel: 19.6 +/- 9.7 mmHg, Amvisc Plus: 20.5 +/- 9.6 mmHg und Healon: 21.8 +/- 8.8 mmHg) was seen. At 24 h IOP was statistically significant higher for Healon than for adatocel and Amvisc Plus (adatocel: 16.3 +/- 4.8 mmHg, Amvisc Plus: 16.5 +/- 4.6 mmHg and Healon: 19.7 +/- 6.6 mmHg). CONCLUSIONS: Six hours postoperatively after phacoemulsification there was no significant difference between the IOP using different viscoelastics adatocel, Amvisc Plus and Healon. Twenty-four hours postoperatively a significantly higher intraocular pressure was measured for Healon than for the other viscoelastics.

Adjuvants, Immunologic↗
PubMed1999

[Endoscopic laser dacryoplasty. Methodology and outcome after 3 months].

BACKGROUND: After performing endoscopy of the lacrimal passage, the endoscopic system can be connected to an erbium-YAG laser if the indications are appropriate. MATERIALS AND METHODS: In a bi-center study we performed laser dacryoplasty in 53 cases out of 261 endoscopy procedures (18 stenoses of the canaliculi, 19 stenoses of the sac, 9 stenoses of the nasolacrimal duct, 9 restenoses following DCR). In 35 cases an examination was done and in all 53 cases the results were obtained by means of a questionnaire. RESULTS: Epiphora and irrigation were improved in more than 75%. CONCLUSION: Suitable indications are small stenoses in the sac or duct membranes following DCR. Laser dacryoplasty is a promising method, but more studies still need to be conducted to obtain long-term results. The technical system must also still be improved to make it easier to handle.

Adult↗
PubMed1998

[Dacryoendoscopy--current status].

UNLABELLED: In the years from 1995 to 1997 in the eyeclinic of Darmstadt and the eyeclinic of the St. Josef Hospital Hagen 261 dacryoendoscopies were done in a bicentrical study. PATIENTS AND METHODS: A dacryoendoscopy was done in 261 patients with an average age of 46.6 years (143 women, 93 men and 25 children). In dependance of the assessment of the mucosa conditions intraoperatively in all 261 cases the planed operative strategy was checked and if needed changed. As following surgical interventions of the lacrimal system were seen 70 cases of dacryocystorhinostomia externa, 138 cases of intubation of the lacrimal drainage system and 53 cases of laserdacryoplastic. RESULTS: The dacryoendoscopy had succeeded as method for the assessment of the mucosa conditions [5, 6]. In a study of 261 dacryoendoscopies an examination of the mucosa was possible in every case. No complications were seen while dacryoendoscopy. With help of the dacryoendoscopy the planed operative strategy was determined. Therefore we had the possibility to choose a minimal invasive operation-procedure in 53 cases. CONCLUSIONS: The dacryoendoscopy is a new important diagnostic development in diagnosis of diseases of the lacrimal drainage system. With help of better developed endoscopy-systems a much better quality of the picture is attainable. The results of the dacryoendoscopy offer the possibility to check the preoperative indication and to optimate the surgical treatment. At last only with help of the dacryoendoscopy these findings could be ascertained in which case a laserdacryoplastic is senseful.

Adolescent↗
PubMed1997

[Dacryoendoscopy and laser dacryoplasty: technique and results].

BACKGROUND: In a bicentrical study in the eye clinic of Darmstadt and the eye clinic of the St. Josef Hospital Hagen 261 dacryoendoscopies were performed until February 1997. MATERIALS AND METHODS: In 261 dacryoendoscopies (143 women, 93 men and 25 children, the average age was 46.6 years). In dependence of the assessment of the mucosa conditions intraoperatively in all 261 cases the planed operative strategy was checked and if needed changed. After surgical interventions of the lacrimal system 70 cases of dacryocystorhinostomia externa were seen 138 cases of intubation of the lacrimal drainage system and 53 cases of laserdacryoplastic. Intubation of the lacrimal system was always performed after laserdacryoplastic and after a patency was produced (average age 58.3 years). RESULTS: Suitable indications for a laserdacryoplastic are: circumscribed stenosis of the distal saccus, point-sized stenosis of the canaliculus, membranous restenosis after dacryocystorhinostomia externa. The method shows no important rate of intraoperative complications, only in one case there was intraoperatively a protrusion bulbi and a haematoma of the eyelid, which postoperatively eased fastly away. The postoperative convalescence is in comparence to conventional surgical interventions of the lacrimal drainage system enormously shortened. The follow-up after 3 months showed a subjective improvement of epiphora in more than 75% of the patients, the success of this intervention therefore could be compared with conventional surgical methods of the lacrimal drainage system. CONCLUSION: The dacryoendoscopy is a new important diagnostic development, which shows with help of better developed endoscopy-systems compared to previous systems a much better quality of the image and is therefore a valuable diagnostic help. Due to the check of the preoperative indication it is intraoperatively possible to confirm or, if needed, to change the indication after dacryoendoscopy. The laserdacryoplastic is an important new therapeutical development of the dacryoendoscopy and shows in suitable indications a comparable success-rate of conventional surgical interventions of the lacrimal drainage system. Therefore the possibility exists to carry out minimal invasive interventions of the lacrimal drainage.

Adult↗
PubMed1994

[Quantification of disorders of the blood-aqueous humor barrier in retinitis pigmentosa--initial results].

BACKGROUND: Clinical findings in patients with retinitis pigmentosa (RP) frequently include cystoid macular edema (CME) and vitreous pigment dusting (VPD) indicating alterations of the blood-ocular barriers. It was the aim of this study to determine whether alterations of the blood-aqueous barrier (BAB) are present in RP. PATIENTS AND METHODS: Aqueous flare was quantitatively determined in 56 eyes of 29 patients (mean age 36.4 +/- 11.2 years) with RP using the noninvasive laser flare-cell photometer (Kowa FC-1000, Tokyo, Japan). All RP patients had common forms of RP with markedly reduced or nondetectable ERG. The presence of CME and VPD was determined semiquantitatively by biomicroscopy. Fifty-eight eyes of 58 normal controls (mean age 38.2 +/- 8.5 y.) were also examined. RESULTS: Aqueous-flare values were significantly higher in RP eyes (mean 9.65 +/- 3.24 photon counts/ms, range 4.0-18.1) than in the normal control eyes (mean 3.89 +/- 1.05, range 1.9-6.0, p < 0.0001, Mann-Whytney test). Forty-eight of the 56 RP eyes (86%) showed increased flare values (> 6.0 photon counts/ms). RP eyes with moderate to marked CME (n = 11) had significantly higher flare values (mean 14.66 +/- 1.92) than RP eyes without or with only questionable CME (8.52 +/- 2.18, p < 0.0001), and RP eyes with moderate to marked VPD (n = 17) had significantly higher (12.05 +/- 2.84) flare values than RP eyes without or with only minimal VPD (8.74 +/- 2.22, p < 0.0005). CONCLUSIONS: Our findings show that the majority of patients with RP have alterations of the BAB with consecutively increased aqueous protein concentrations. The impairment of the BAB appears to be associated with CME and VPD. Measurement of aqueous flare in RP allows quantification of the impairment of the BAB and may be helpful in the future in choosing and monitoring patients with RP and CMP for possible antiinflammatory or antiedematous therapeutic measures.

Adult↗