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Biomedical subjects

M Labrune

Publications and source records attributed to M Labrune.

At least 19 recordsLinked to original sources

Magnetic excitations in a weak-stripe-domain structure: A 2D dynamic micromagnetic approach

The high-frequency susceptibility spectra of ferromagnetic films supporting a weak-stripe-domain structure are computed using a 2D dynamic micromagnetic model that we have developed. The existence of multiple resonances resulting from the excitation of surface and volume modes is predicted. The main features of spectra (number of resonances, resonance frequencies, intensities, and linewidths) strongly depend on the equilibrium spin configuration and on the rf exciting field orientation. These theoretical results are successfully compared with zero-field microwave permeability measurements.

Journal Article↗

Magnetic resonance imaging of the fetus: a study of 20 cases performed without curarization.

Twenty patients underwent magnetic resonance imaging (MRI) at a mean gestational age of 32 weeks. There were 12 patients with suspected fetal brain abnormality and four with intrauterine growth retardation (IUGR), while the remaining four cases were studied for other reasons. The MRI examinations were performed on a 0.5 Tesla machine, with surface coils. One minute acquisition time T1 sequences were used. All the studies were performed without fetal curarization, and only under maternal sedation using flunitrazepam given per os 1 h before MRI examination. Three examinations were incomplete because of fetal movement artefacts. In the remaining cases, MRI allowed the examination of fetal brain anatomy. In five cases, it helped to differentiate isolated hydrocephalus and corpus callosum agenesis. Sub-ependymal nodules were depicted in a case of fetal tuberous sclerosis. One suspected arachnoid cyst was proved to be an ultrasound artefact. Decreased fetal fat on MR images was correlated with low birth weight in cases of IUGR. Due to its better spatial resolution, ultrasonography was more accurate for the diagnosis of facial and lumbar anomalies. Fetal MRI may be performed without curarization. Surface coils allow the detailed analysis of brain parenchyma, and thus MRI is especially useful in the difficult prenatal diagnosis of fetal brain abnormalities.

Adipose Tissue↗

Acute pulmonary embolism: diagnostic value of digital subtraction angiography.

Digital subtraction angiography (DSA) performed via a peripheral vein was compared prospectively with selective conventional pulmonary angiography (CPA) in 54 patients suspected of having pulmonary embolism (PE). All patients also underwent ascending venography. In contrast to the conventional pulmonary angiograms, all of which were considered satisfactory, 13 of 54 digital subtraction angiograms (24%) were technically unsatisfactory. The interpretable digital subtraction angiograms had 81% sensitivity and 64% specificity. With DSA, one cannot exclude the diagnosis of PE on the basis of normal angiograms (27% false-positive results) as one can with perfusion scanning. On the other hand, DSA showed good sensitivity (94%) in medium to major PE. Therefore it may be the technique of choice in the screening of life-threatening PE for which curative emergency treatment with thrombolytic agents or embolectomy is often necessary.

Acute Disease↗

[Transfontanelle echography: correlation with anatomopathological data. Apropos of 39 cases in newborn infants].

Thirty-nine neonates including 29 prematures had correlation studies of trans-fontanelle ultrasounds with post-mortem anatomic findings. Occipital hyper-echogenicity can be physiological when it is symmetric in the premature infant, and may indicate ischemia and/or anoxia when it is asymmetrical. No abnormal pathology went undetected by echo. Cortical gyri were never seen prior to 32 weeks gestational age.

Cerebral Hemorrhage↗

Early echographic findings in non-hemorrhagic periventricular leukomalacia of the premature infant.

The ultrasonic detection of periventricular leukomalacia is described in two neonatal patients. Confirmation of this condition by CT and post mortem was obtained in one case. CT scan and further echography was positive in the other. Neither patient had evidence of an intracranial hemorrhage. It is suggested that echography is of value in the early diagnosis of this lesion which may be similar to intraparenchymal hemorrhage in its mechanism and prognosis.

Brain Diseases↗

Sonography in the diagnosis and follow-up of pancreatic pseudocysts in childhood. A report of 4 cases.

Pancreatic cyst disease is rare in children and pseudocysts are in general post traumatic. The authors present four cases of pancreatic pseudocysts in children aged from 2 to 12 years, seen in Institut National de Santé de l'Enfance (Tunis) and in Hôpital Antoine Beclère in Clamart (France). All were verified by surgery. The diagnosis was not established before echography. The authors present the echographic patterns of this rare condition and review the literature. The contribution of the sonographic examination in the diagnosis of the pancreatic cyst in children and in the follow-up of the patients is emphasised.

Child↗

[Shwachman's syndrome with neonatal thoracic manifestations].

The authors report a case of Shwachman's syndrome in whom neonatal respiratory distress was the initial manifestation. Metaphyseal dysplasia, which was severe at birth, progressively disappeared. By the age of 10 years, radiologic anomalies persist only in the pelvis.

Agranulocytosis↗

[Caffey's disease with antenatal onset].

The authors report one case of Caffey's syndrome with antenatal onset. X-ray of the uterus, that was required because of an hydramnios, led to the diagnosis. Ultrasonography showed the fetal anomalies. Data in the literature concerning case reports of Caffey's syndrome with antenatal onset show a moderate incidence of familial cases.

Female↗

[Urinary tract obstruction and histiocytosis X : a report on 3 cases (author's transl)].

Three cases of histiocytosis X are reported in which urographic modifications suggested the presence of an obstruction. Similar cases do not appear to have been described in the published literature, and renal changes previously reported as occurring during histiocytosis X affections have all been based on autopsy findings. The possible role of diabetes insipidus in the dilatation of the excretory cavities is also envisaged.

Adult↗