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Biomedical subjects

M Lanzetta

Publications and source records attributed to M Lanzetta.

59 records · Page 4Linked to original sources
PubMedDate not supplied

[Comparison of treatment techniques of rhizarthrosis of the thumb. Apropos of a series of 98 cases].

We compared 3 methods of treatment of trapezometacarpal arthritis: partial trapezectomy with Ashworth Blatt interposition and total trapezectomy with either Swanson spacer or anchovy procedure. Out of a series of 85 patients (98 operations), 52 (62 operations) were reviewed by an independent observer after a mean follow-up of 5 years. Silicone spacers were frequently complicated by subluxation, fragmentation and silicone synovitis. All procedures were effective on pain and mobility. Best results on strength were observed after trapezectomy with anchovy interposition and ligamentoplasty.

Adult↗
PubMedDate not supplied

In vitro laser nerve repair: protein solder strip irradiation or irradiation alone?

BACKGROUND: This study investigated the potential of sutureless nerve repair using two promising laser fusion methods: direct 2 microns irradiation of the epineurium, and protein solder assisted epineurial fusion using a 800 nm laser. MATERIALS AND METHODS: Laser anastomosis of the rat sciatic nerve was performed in vitro without stay sutures in two groups of six animals. In the first group, direct laser fusion used a pulsed Cr, Tm: YAG laser. In the second group an albumin-based fluid solder containing the dye indocyanine green was applied to the epineurium, then irradiated with a diode laser. These two techniques were compared with regards to coaptation success and axonal damage. RESULTS: Direct laser welding produced weak bonds despite microscopic investigation of the irradiated nerves showing fusion of the epineurium. The unsatisfactory bonding can be attributed to poor tissue overlap and insufficient protein in the thin epineurium denaturation of underlying axons was also observed. In contrast, the laser solder method produced successful welds with greatly reduced axonal damage, and significantly improved the tensile strength. CONCLUSIONS: This study confirmed the technical possibilities of sutureless nerve anastomosis. Laser activated solders enable stronger bonds, by the addition of protein to the anastomosis site, and less thermal damage to underlying tissue through selective absorption of laser energy by dye in the solder. Further in vivo studies are required before drawing final conclusions.

Anastomosis, Surgical↗