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Biomedical subjects

M Lavieuville

Publications and source records attributed to M Lavieuville.

12 recordsLinked to original sources
PubMed1980

[Reversible lactic acidosis in a diabetic on high dose metformin (author's transl)].

In a diabetic, who took a high dose of 5.85 g metformin daily for 75 days, urinary retention caused by a prostatic adenoma induced functional renal insufficiency and hyperlactacidemia, rapidly reversed with treatment. Plasma and urine levels of metformin were measured at the same time as lactate and pyruvate levels, until all returned to normal. Clinical and biological improvement occured at the same time. The case is discussed in the context of lactic acidosis in diabetics with functional or organic renal insufficiency, treated with metformin.

Adenoma↗
PubMedDate not supplied

[Effect of veinotonyl 75 on the capillary permeability test using technetium albumin in cyclic orthostatic edemas].

The purpose of this trial was to evaluate the clinical effect of Veinotonyl 75 in 42 women, 42 +/- 11 years old, with orthostatic cyclic edema. The main evaluation criterion was the result of a capillary filtration test with 99 mTc albumin which was performed at day 0 and at day 30 after treatment. At day 0, all the women had abnormal results ie an albumin retention > or = 8% (mean: 14.3% +/- 4.8%). At day 30, 75% of the patients were normalized in the Veinotonyl 75 group versus 38% in the placebo group (p < 0.02). The albumin retention in Veinotonyl 75 group was under the pathological level (mean: 5.2% +/- 4.8%) while it was over in the placebo group (mean: 9.4% +/- 7%). This study confirms the activity of Veinotonyl 75 on capillar protein hyperfiltration and on return venous circulation.

Adult↗